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The Use of Methods of the Project management in Company
Šima, Michal ; Doskočil, Radek (referee) ; Smolíková, Lenka (advisor)
The content of bachelor thesis is the use of project management tools and PRINCE2 methodology in practice. The main goal is to create a project plan for the implementation of a new tool designed to collect feedback data from customers in a particular company. At the beginning of the thesis, basic concepts such as project, project management, project life cycle or PRINCE2 methodology are described. The second part is focused on the analysis of the current state of the company with its summary in the SWOT analysis. In the last part, a project proposal with the application of the PRINCE2 methodology and its structure tailored to the environment and the needs of the company is compiled.
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Application of Agile Methodologies in Selected Company
Šima, Michal ; Smolíková, Lenka (referee) ; Doskočil, Radek (advisor)
The diploma thesis deals with the application of agile methods, with the goal of increasing the efficiency of project management flow, in a specific company that focuses on web application development. Preparing a suitable project management change proposal will help the company better integrate agility into its processes, increase implementation efficiency, and the ability to respond more flexibly to the rapidly changing needs of its customers.
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Application of Agile Methodologies in Selected Company
Šima, Michal ; Smolíková, Lenka (referee) ; Doskočil, Radek (advisor)
The diploma thesis deals with the application of agile methods, with the goal of increasing the efficiency of project management flow, in a specific company that focuses on web application development. Preparing a suitable project management change proposal will help the company better integrate agility into its processes, increase implementation efficiency, and the ability to respond more flexibly to the rapidly changing needs of its customers.
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Identification, expression, and characterization of Phlebotomus orientalis salivary antigens
Šíma, Michal ; Kolářová, Iva (advisor) ; Gomes, Regis (referee) ; Chmelař, Jindřich (referee)
Sand flies (Diptera: Psychodidae) are vectors of Leishmania spp. (Kinetoplastida: Trypanosomatidae), medically and veterinary important parasites causing leishmaniasis. These protozoans are inoculated into the host during blood-feeding together with the vector saliva. Salivary components are crucial for sand fly female blood-sucking but also play a major role in the initial stage of parasite development. It was demonstrated that this rich mixture of proteins performs different functions after its injection into the host like hydrolyzing ATP and ADP, binding biogenic amines, and others which inhibits the haemostatic reaction and modulate the immune system thus enables the successful feeding. So far, cDNA salivary transcriptomes have been constructed for twelve sand fly species and we added another one - Phlebotomus orientalis, the main vector of Leishmania donovani, a causative agent of human visceral leishmaniasis in East African countries. We described members of thirteen protein families which corresponded with previously published salivary cDNA libraries of other sand fly species and showed the main salivary antigens using sera of experimentally bitten mice and naturally exposed dogs. Specific IgG antibody response is induced against sand fly salivary proteins in repeatedly bitten hosts....
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Identification, expression, and characterization of Phlebotomus orientalis salivary antigens
Šíma, Michal
Sand flies (Diptera: Psychodidae) are vectors of Leishmania spp. (Kinetoplastida: Trypanosomatidae), medically and veterinary important parasites causing leishmaniasis. These protozoans are inoculated into the host during blood-feeding together with the vector saliva. Salivary components are crucial for sand fly female blood-sucking but also play a major role in the initial stage of parasite development. It was demonstrated that this rich mixture of proteins performs different functions after its injection into the host like hydrolyzing ATP and ADP, binding biogenic amines, and others which inhibits the haemostatic reaction and modulate the immune system thus enables the successful feeding. So far, cDNA salivary transcriptomes have been constructed for twelve sand fly species and we added another one - Phlebotomus orientalis, the main vector of Leishmania donovani, a causative agent of human visceral leishmaniasis in East African countries. We described members of thirteen protein families which corresponded with previously published salivary cDNA libraries of other sand fly species and showed the main salivary antigens using sera of experimentally bitten mice and naturally exposed dogs. Specific IgG antibody response is induced against sand fly salivary proteins in repeatedly bitten hosts....
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The Use of Methods of the Project management in Company
Šima, Michal ; Doskočil, Radek (referee) ; Smolíková, Lenka (advisor)
The content of bachelor thesis is the use of project management tools and PRINCE2 methodology in practice. The main goal is to create a project plan for the implementation of a new tool designed to collect feedback data from customers in a particular company. At the beginning of the thesis, basic concepts such as project, project management, project life cycle or PRINCE2 methodology are described. The second part is focused on the analysis of the current state of the company with its summary in the SWOT analysis. In the last part, a project proposal with the application of the PRINCE2 methodology and its structure tailored to the environment and the needs of the company is compiled.
|
|
|
Identification, expression, and characterization of Phlebotomus orientalis salivary antigens
Šíma, Michal ; Kolářová, Iva (advisor) ; Gomes, Regis (referee) ; Chmelař, Jindřich (referee)
Sand flies (Diptera: Psychodidae) are vectors of Leishmania spp. (Kinetoplastida: Trypanosomatidae), medically and veterinary important parasites causing leishmaniasis. These protozoans are inoculated into the host during blood-feeding together with the vector saliva. Salivary components are crucial for sand fly female blood-sucking but also play a major role in the initial stage of parasite development. It was demonstrated that this rich mixture of proteins performs different functions after its injection into the host like hydrolyzing ATP and ADP, binding biogenic amines, and others which inhibits the haemostatic reaction and modulate the immune system thus enables the successful feeding. So far, cDNA salivary transcriptomes have been constructed for twelve sand fly species and we added another one - Phlebotomus orientalis, the main vector of Leishmania donovani, a causative agent of human visceral leishmaniasis in East African countries. We described members of thirteen protein families which corresponded with previously published salivary cDNA libraries of other sand fly species and showed the main salivary antigens using sera of experimentally bitten mice and naturally exposed dogs. Specific IgG antibody response is induced against sand fly salivary proteins in repeatedly bitten hosts....
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Host specificity, diversity and distribution of avian malaria parasites in a contact zone of two nightingale species
Šíma, Michal ; Munclinger, Pavel (advisor) ; Sádlová, Jovana (referee)
Avian contact zones were suggested to act as barriers to parasite expansions. I studied haemosporidian parasites (genera Plasmodium, Haemoproteus, and Leucocytozoon) of two Nightingale species which meet in a contact zone in Europe. In total 20 lineages of parasites were detected. Surprisingly, all common lineages were shared by the two host species. The parasite prevalence vary between species (Trush Nightingales were more often parasitized than Common Nightingales.) but did not vary to a large extent within zones inside species Parasitemia of the most frequent Haemoproteus LULU1 lineage assessed by Real-Time PCR method did not differ significantly between the two host species. Six out of nine hybrids of the nightingale species were parasitized. Haemosporidian lineages found in hybrids were also frequent in the parental species. In conclusion, the nightingale contact zone seems to have only little (if any) effect on the distribution of haemosporidian parasites.
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Identification, expression, and characterization of Phlebotomus orientalis salivary antigens
Šíma, Michal
Sand flies (Diptera: Psychodidae) are vectors of Leishmania spp. (Kinetoplastida: Trypanosomatidae), medically and veterinary important parasites causing leishmaniasis. These protozoans are inoculated into the host during blood-feeding together with the vector saliva. Salivary components are crucial for sand fly female blood-sucking but also play a major role in the initial stage of parasite development. It was demonstrated that this rich mixture of proteins performs different functions after its injection into the host like hydrolyzing ATP and ADP, binding biogenic amines, and others which inhibits the haemostatic reaction and modulate the immune system thus enables the successful feeding. So far, cDNA salivary transcriptomes have been constructed for twelve sand fly species and we added another one - Phlebotomus orientalis, the main vector of Leishmania donovani, a causative agent of human visceral leishmaniasis in East African countries. We described members of thirteen protein families which corresponded with previously published salivary cDNA libraries of other sand fly species and showed the main salivary antigens using sera of experimentally bitten mice and naturally exposed dogs. Specific IgG antibody response is induced against sand fly salivary proteins in repeatedly bitten hosts....
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