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Landscape memory in the memory of its inhabitants - Dolní Hbity district
Fialová, Kristýna ; Zelinka, Vít (advisor) ; Václav, Václav (referee)
The name of the thesis is: Cadastral Area of Dolní Hbity s Landscape in Memories of its Inhabitants. The thesis aims to map changes in this particular landscape. In order to realizing those changes it was necessary to settle main trends and how they impacted the area of Dolní Hbity. The main body part of the bachelor thesis bases on primary changes realized from the available sources and maps, with addition of res-pondent answers. Firstly, the thesis introduces common literature, knowledge and information, which are consequently used in researching the changes. The second part is researching the actual changes and creating analysis of landscape, based on ČÚZK data, available maps, which are compared to the respondents answers. Or-tophotomaps, from 1948 and 2014, are used as the main source, and additionally available information about the area sizes, with comparison of respondents answers. Those sources are evaluated each other, the result forms united analysis of changes in the particular landscape, which helps observe changes and movements in the land-scape, which actually happened during the observed time period.
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Child's nursery school adaptation impact of social enviroment
FIALOVÁ, Klára
The bachelor thesis deals with an issue if the social environment which a child comes from into nursery school has an impact on child's adaptation. The thesis defines socialization, social environment, culture, family, foster family care and different adaptation. The practical part of this thesis submits the results of observed children from different social environment in chosen areas. Additional information were gained from questionnaires for parents about their children. During the investigation the process of adaptation was described due to the social environment the child grows in. The main aim of this thesis was to find out if there are some differences between the children, how the problems are manifested and what the causes of them are.
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Cutting ceramics and its effective use
Fialová, Kateřina ; Prokop, Jaroslav (referee) ; Humár, Anton (advisor)
The diploma work is focused on the ceramic tool materials and its effective use. The introductory part of the work contains the detail characteristic of the ceramic tool materials from the point of view of their dividing, physic-mechanical propertis, production methods and marking. The main part of the work is focused to judging of the ceramic portion at the production assortment of the top World producers of tool materials and to evaluation of cutting ability of the particular materials of these producers. The detail analysis of recommended cutting conditions, which is aimed to an effective use of the ceramic materials, had been worked up for this purpose. The technical economic analysis confirms, that the present effective aplications of ceramic are limited only for specific cases of machining cast irons, steels and alloys.
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SWOT analysis of non profit organization
Borsuková, Lucia ; Vávrová, Hana (advisor) ; Fialová, Karolína (referee)
The aim of this thesis is to provide a SWOT analysis of the Via Foundation through which is detected potential opportunities and threats for the organization and its current strengths and weaknesses. The theoretical part explains the basic concepts, theoretical knowledge and the process itself concerning the creation of a SWOT analysis. The described methods are then used in the practical part on the example of the Via Foundation. To identify potential opportunities and threats from the external environment is used PEST analysis supported by time series analysis. For discovering potential of the organization in terms of strengths and weaknesses is used the evaluation of selected parameters of the organization as compared to the analogous organizations. In conclusion, the thesis summarizes important information obtained by this analysis and there are proposed recommendations for the organization.
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Analysis of financing of the non-profit sector in the Czech Republic
Fialová, Karolína ; Potluka, Oto (advisor) ; Špaček, Martin (referee)
This thesis focuses the financing of non-governmental organizations. The main part is devoted to financial sources which can use Czech non-profit organizations (NGOs). Fundraising is how NGOs get financial and non-financial support. The practical part consists of an analysis of financial sources and survey among NGOs. The aim is to analyze selected changes that influence non-profit organizations and their fundraising activities. An economic crisis had a significant impact on non-profit organizations. It has slightly changed the structure of financial resources. Although there was an increase in own revenues, government grants are still the dominant source. Importance of European funds also grows. The new Civil Code which came into force on 1 January, 2014 can strengthen individual and corporate donations.
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Leiden mutation, its signification and methods of examination
FIALOVÁ, Kateřina
The subject of this thesis is Leiden mutation, its signification and methods of examination. This work deals with frequency of occurrence F V Leiden mutation in samples of examinants in the centre of laboratory medicine BioLab, spol. s. r. o., in Klatovy. Thrombophilia (hypercoagulation) is a genetic or acquired failure of hemostatic mechanistic system, which is connected with increased risk of the occurrence of thrombosis. The most important and the most frequent effect of thrombophilia is the venous thromboembolism. This concept means both deep venous thrombosis and/or pulmonary embolism and their development is always caused by several factors which are genetic or acquired. Mutation of factor V was described in 1993 as the resistance against activated protein (so called APC-resistance). It occurs most commonly as a genetic thrombophilia of white race where it can be found in 40% of patients with diagnosed thromboembolism. Leiden mutation in a gene for factor V is the most frequent predisposition for thrombosis. The risk of development of venous thromboembolism differs according as the fact if it is a heterozygotic or homozygotic carrier. Heterozygotic individuals are 7 times more riskly as for the development of venous thrombosis while the risk level in homozygotic individuals is 80 times. The rate of prevalence of FV Leiden mutation in the world ranges from 0 to 15 %. APC- resistance is caused by point mutation in the polynucleotide chain of a gene for factor V. Here it concerns the exchange of the nucleotide sequence respectively nitrogen basis of guanine and adenine for the position 1691 (G1691A). It creates a triplet which codes in position 506 in the place of amino acid arginine -Arg, R, glutamine -Gln, Q(R506Q). It causes resistance of the active factor V against protein C, which is to inactivate it. The factor V stays henceforth pro- coagulative and thus the creation of thrombin increases together with the risk of thromboembolic disease. The goal of this thesis was summarising of research findings related to the focused theme Leiden mutation, its signification and methods of examination, analyze whole blood samples of patients examined at Leiden mutation carrier status in the center of Laboratory Medicine BioLab, spol. s. r. o. in Klatovy and in consequence and then evaluate and interpret the results of the found out results. Carrier of FV Leiden mutation was observed in a group of patients of both sexes coming from Plzeň and Ústí nad Labem region using real-time PCR. Of the 169 patients examined 111 samples were obtained from women and 58 samples from men. Among women there were found 21 heterozygous carriers (18.9%) and 1 homozygous carrier of (0.9%) FV Leiden mutation. The male population was observed incidence of 17 heterozygotes (29.3%). None of the men did not hold the homozygous genotype FV Leiden mutation. Although the men were twice as frequent carriers of that mutation was not statistical analyzes demonstrated the effect of gender on the transfer FV Leiden mutation (P = 0.2).
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