|
|
Benchmark of the Computational Tools for the Prediction of the Effect of Mutations on Protein Stability
Berezný, Matej ; Martínek, Tomáš (oponent) ; Musil, Miloš (vedoucí práce)
Protein design necessitates understanding how mutations influence their stability. Numerous online predictors exist for this aim, but it is challenging to compare them or to use them collectively. For that purpose I developed BenchStab, a console application/Python package designed for the swift and straightforward operation of 18 predictors, gathering results from a series of mutants. Benchstab is freely available on GitHub and can be expanded to include more predictors. To avoid potential dataset bias towards some predictors, I have constructed a new unique dataset, sourced from FireProtDB. I utilized this dataset to assess 24 distinct prediction methods from the three different perspectives.
|
|
|
Performance Testing and Analysis of Qpid Dispatch Router
Stejskal, Jakub ; Rogalewicz, Adam (oponent) ; Fiedor, Tomáš (vedoucí práce)
Application performance testing has recently become more important during the application development of all kinds. This paper maps the fundamentals of performance testing that are commonly used and it analyzes performance testing of components used in Messaging systems, especially Apache ActiveMQ Artemis and Qpid-Dispatch. However, currently used methods for performance testing of these components are primarily focused only on Apache ActiveMQ Artemis by system Messaging Performance Tool called Maestro. This paper proposes improvements of Messaging Performance Tool to allow proper performance testing of Qpid-Dispatch and its capabilities in automatic testing. The solution is demonstrated on series of experiments with different topologies. The final report evaluates the proposed application, the performance of Qpid-Dispatch component and develops ideas for future works.
|
|
|
Performance Testing and Analysis of Qpid Dispatch Router
Stejskal, Jakub ; Rogalewicz, Adam (oponent) ; Fiedor, Tomáš (vedoucí práce)
Application performance testing has recently become more important during the application development of all kinds. This paper maps the fundamentals of performance testing that are commonly used and it analyzes performance testing of components used in Messaging systems, especially Apache ActiveMQ Artemis and Qpid-Dispatch. However, currently used methods for performance testing of these components are primarily focused only on Apache ActiveMQ Artemis by system Messaging Performance Tool called Maestro. This paper proposes improvements of Messaging Performance Tool to allow proper performance testing of Qpid-Dispatch and its capabilities in automatic testing. The solution is demonstrated on series of experiments with different topologies. The final report evaluates the proposed application, the performance of Qpid-Dispatch component and develops ideas for future works.
|
host ::
RSS.