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Torture prohibition in international law
Šupová, Tereza ; Honusková, Věra (advisor) ; Faix, Martin (referee)
Prohibition of torture in the international law The prohibition of torture and other forms of ill-treatment is universally recognized and is enshrined in all of the major international and regional human rights instruments. It is also a firmly rooted principle of customary international law, and as such, it is binding on all states at all times. All international instruments that contain the prohibiton of torture and ill- treatment recognize its absolute, non-derogable character. The purpose of my thesis is to analyse how views regarding torture have changed. I have focused on torture cases in last twenty years. Are people tortured more than in the past? In which countries is the situation worst? I specialised on european continent and on judgements of The European Court of Human Rights. I was trying to find out how many cases The European Court was dealing with and what treatment can be classified as torture or inhuman or degrading treatment or punishment. I have also asked the question if the understanding of what is torture has changed from the year 1991 until 2010. The thesis is composed of six chapters, first part is introduction, the second one mentions international and regional documents, in which prohibition of torture was recognized. The Third Chapter defines basic terminology used in the thesis....
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A novel approach for description of non-covalent intermolecular interactions
Rubeš, Miroslav ; Bludský, Ota (advisor) ; Fišer, Jiří (referee) ; Jurečka, Petr (referee)
Charles University in Prague Faculty of Science Department of Modeling of Chemical Properties of Bio- and Nanostructures A novel approach for description of non-covalent intermolecular interactions Dissertation Thesis Abstract Mgr. Miroslav Rubeš Supervisor: RNDr. Ota Bludský, CSc. Institute of Organic Chemistry and Biochemistry AS CR Center for Biomolecules and Complex Molecular Systems Prague 2010 Introduction Non-covalent interactions play a major role in many important physical, chemical, and biological processes that include, for instance, inter-molecular interactions between biomolecules, adsorption and separation, self-assembly in supra-molecular chemistry, and catalytic activity. To gain a deeper understanding of such processes at the atomistic level it is often necessary to investigate these systems theoretically. Due to the complex character of relevant systems, realistic models include hundreds of atoms and, thus, the computational investigation must rely on rather approximate methods. An accurate description of these systems still represents a major challenge for theoretical chemists. Methods based on density functionals (density functional theory, DFT) are currently among the most popular approaches for computational treatment of large systems. Unfortunately, the non-covalent interactions...
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Case study physiotherapy treatment of patients with diagnosis: Gangrene pedis bilaterally, frostbite, TMT - amputation under general anaesthesia.
Günterová, Lucie ; Křížková, Štěpánka (advisor) ; Kučerová, Ilona (referee)
Case study: Physiotherapy treatment of patients with the diagnosis: Bilateral pedis gangrene, frostbite TMT - amputation in CA. Content is focused on rehabilitation after amputation of fingers on both lower limbs due to frostbite in the advanced stages of necrosis and subsequent amputation. The aim is to introduce the amputation of the foot, studying literature and the use of theoretical and practical knowledge gained during their studies. Objective description of physiotherapy sessions and a description of the recorded physiotherapy techniques, procedures and examinations. In addition, ensure quality care, improve health, practice self- care and walk carefully chosen treatments. The general section contains a description of the anatomy, kinesiology and biomechanics of lower extremity peripheral. A short introduction to the terms of amputation, frostbite, necrosis, phantom pain, orthotics - prosthetics. Description of the methods, techniques and tests. The practical part of the special assessment is an evaluation of the initial examination, the course of therapy and final examination with subsequent evaluation of the effect of therapy. Bachelor's thesis can be used for students to approach the problem of amputations or patients themselves and their relatives in coping with this disability. Key...
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The importance of myofeedback rehabilitation in faecal incontinence
Černovská, Markéta ; Nováková, Tereza (advisor) ; Neuwirthová, Svatava (referee)
Title: The importance of myofeedback rehabilitation in faecal incontinence Introduction: Faecal incontinence is a serious symptom significantly worsening quality of life. Following results of international studies myofeedback has been considered an effective option of conservative treatment of this disease. Despite that it has so far been used at just a few centres in the Czech Republic. Purpose: The main purpose of this thesis was to assess the relevance of myofeedback as part of recovery therapy. Other objectives included assessment of use of a vaginal electrode instead of an anal one and comparison of the result correlations between examination by anal manometry, surface EMG and subjective improvement of continence for the patients. Methods: The research project included 8 females. The objective method of assessment of effects of the treatment involved examination of pelvis bottom muscles with the help of anorectal manometry and surface EMG. Success of the therapy was evaluated through the St Marks incontinence score and by the test population themselves filling out a quality of life questionnaire. Results: In the course of three-month recovery most patients experienced improvement of subjective as well as objective parameters. The results of the study are comparable to results of international...
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Evaluation of cardiorespiratory capacity of sportsmen and obese patients measured by spiroergometry (Oxycon)
Kieu Thi, Thanh Hai ; Vilikus, Zdeněk (advisor) ; Nguyen, Hong Vu (referee)
The objective of this thesis is to evaluate the cardiorespiratory fitness of sportsmen and obese patients through the medium of spiroergometry on cycloergometer by virtue of the analyzer of exhaled gas (Oxycon). Its advantage is that the measurement takes place "on- line", therefore it allows prompt monitoring of measured spiroergometric parameters directly on screen of computer that forms part of the analyzer. The spiroergometry is a method of determining the cardiorespiratory fitness through the medium of analyzer of exhaled gas in order to state the physical fitness. For statistical evaluation of differences in values of spiroergometric indicators between these two observed groups of patients I used the Student's unpaired T-test. The theoretical part contains an introduction into the issue of obesity, obesity epidemiology, history, aetiology and health risks of this disease, classification, diagnostics, treatment, and recommendations and advices for patients. Furthermore it contains terms as sports medicine, influence of motional activity on human organism, cardiorespiratory fitness, spiroergometry methodology, and spiroergometric parameters. The practical part contains a description of spiroergometric measuring process at the Institute of Sports Medicine at the 1st Faculty of Medicine of the...
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The preparation of recombinant tau protein and it's usage for the detection of Alzheimer disease
Kolářová, Michala ; Hofbauerová, Kateřina (advisor) ; Fialová, Lenka (referee)
Currently a grate emphasis is being put on accurate and early diagnosis of Alzheimer's disease (AD), which is important for the introduction of treatments that could postpone the onset of the disease. Antibodies against tau protein appear to be suitable biomarkers for early diagnosis of AD. Therefore, this work deals firstly with preparation of human recombinant tau protein in bacteria and its subsequent use in determining levels of antibodies in blood serum of patients with AD and in normal older persons. A preparation of the tau protein in sufficient purity was achieved for the antibodies measurment by ELISA method and results were statistically analyzed using nonparametric methods. Results were compared with data from Mgr. Jany Švarcové obtained by measuring antibodies in serum of patients with AD and normal elderly using an commercial bovine tau protein. According to the analysis there are differences between the data obtained from human and the bovine tau protein. It was proven that patients with AN have lower levels of antibodies against tau protein than healthy seniors. Recombinant human tau protein was also used to immunize rabbits. The ELISA method confirmed the creation of antibodies against human tau protein in rabbits.
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Electrotactile sensory substitution in patients with degenerative cerebellar ataxia
Svojítková, Tereza ; Čakrt, Ondřej (advisor) ; Paulasová - Schwabová, Jaroslava (referee)
Introduction: Biofeedback based on sensory substitution is a new method to treat patients with postural disorders. BrainPort provides tongue electrotactile stimulation. This innovative technique was developed for vestibular dysfunction of peripheral origin. Primarily for patients who had no benefits from conventional rehabilitation. Tongue electrotactile stimulation seems to be useful for central vestibula dysfunction as well. We are dealing with effect of BrainPort in therapy of degenerative cerebellar ataxia. We are interested in whether the effects persist for one month after the rehabilitation program. Methods: The methods are applied in 6 patients with degenerative cerebellar ataxia, verified by clinical testing, posturography, and genetic testing or verification of cerebellar lesions by MRI. Patients underwent an 12-day intensive rehabilitation program with BrainPort. Treatment was carried out 2 times a day. Patients were learning appropriate postural corrections to maintain signal in the middle of the tongue. To assess the effect of therapy we used posturography, standardized clinical tests - BESTest, Dynamic Gait Index (DGI) and standardized questionnaires - The Activities-Specific Balance Confidence Scale (ABC) and Dizzines Inventroy Handicap (DHI). The examination was performed before...
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Prostatic cancer and possibilities of prediction of early success of radical prostatectomy
Svačina, Jakub ; Hanuš, Tomáš (advisor) ; Zachoval, Roman (referee)
Classification of adenocarcinoma prostatae is very important for the treatment. I have described the disease, its treatment and classification in the introduction. I have analysed a sample of 52 patients from the Urological Clinic of General Faculty Hospital. Simple statistics was used for comparing and analysing of relation of preoperative classification and postoperative development of PSA. I have compared preoperative and operative Gleason's score. Preoperative Gleason score underscores the operative score. PSA decrease is significantly higher in patients with high initial PSA and in patients with classification T2N0M0. PSA one month after surgery does not differ in patients with classification T1C and T2 and it does not correlate with the preoperative characteristics of patients. The decrease of PSA is perhaps dependent only on the surgical treatment. Effect of operation cannot be predicted by Gleason score and by age. These results are valid only for patients undergoing radical prostractomy
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Comedic elements in Shakespere's tragedies
Severinová, Klára ; Nováková, Soňa (referee) ; Hilský, Martin (advisor)
The aim of the thesis is to discuss the comedic elements in Shakespeare's five tragedies, Romeo and Juliet, Hamlet, Othello, Macbeth and King Lear. The Introduction presents the elements which I will try to cover in each of the play. Since the treatment of the elements is different play from play, its extent will differ accordingly. I would like to emphasize the existence of the comedy within the genre of tragedy and thus point out on the style which made Shakespeare a well read playwright for over centuries.
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