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Correlation of thyroid autoantibodies and sonographical image in pregnant and non-pregnant women with history of spontaneous abortion
Bartáková, Jana ; Stejskal, Richard (referee) ; Potluková, Eliška (advisor)
Introduction: Autoantibodies against thyroperoxidase (TPOAb), thyroid ultrasound (US) and laboratory assessment of thyroid function are crucial in the diagnostics of autoimmune thyroid disorders (AITD). The aim of this project was to analyse the relationship between TPOAb and US findings in pregnant women and in women after spontaneous abortion (SpA). Methods: Using a self-developed classification system for semi-quantitative assessment of thyroid disorders we analysed data of 186 pregnant women screened positive for thyroid disorders during first trimester of pregnancy and 119 women with history of recent early SpA. Statistical analysis was performed using Chi-square, Mann-Whitney and ANOVA tests. Results: Nearly half of the positively screened pregnant women had normal thyroid US (86/186, 46,2 %); thyroid nodules were found in 34 (18,3 %) and US signs of AITD in 66 (35,5 %). More than half of the TPOAb-positive pregnant women had normal thyroid US (71/131, 54,2 %). However, normal thyroid US was found only in 2/12 (16,6 %) of TPOAb-positive women after SpA (p=0,029). Pregnant women with pathological thyroid US had significantly higher serum concentrations of TPOAb compared to women with normal US (1487 kIU/l vs. 354 kIU/l; p<0,001). Furthermore, pregnant TPOAb-positive women with US signs of AITD had a...
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Influence of the contrast medium iodine concentration on quality of the CT examination
RANŠOVÁ, Pavlína
Our work focused on determining absolute and relative density of various contrast agents in relation to iodine contents using in vitro and in vivo methods. It was documented that the relative density of contrast agents increases with the decreasing contents of iodine, i.e. density absolute values vary inversely as iodine content in these substances. Four various agents, bearing commercial names Visipaque 270, Visipaque 320, Ultravist 370 and Iomeron 400, in their original glass packing were used for our in vitro measurements. The measurements were carried out using CT equipment Emotion Duo (Siemens, Forchheim, Germany). Individual packing of the contrast agents were scanned by means of a standard protocol and under standard conditions. The obtained data were entered into tables. A retrospectively selected array of patients with standard scan of their stomachs was used for our in vivo measurements with a defined standard protocol using the same CT equipment and pressure injector CT 9000 Advantage (Liebel-Flarsheim, Mallinckrodt, the U.S.A.). The following data from 258 patients were recorded: age, sex, blood density after administering contrast agent in vitro on the level of diaphragm hiatus and on the bifurcation level, AP dimension of the patients on the hiatus level. Mean densities of the individual kinds of contrast agents were compared and a good correlation with the in vitro measurements was found out. The measured values were then analysed. The interdependence was studied in the measured densities and age, density changes measured on the hiatus level and on the bifurcation level for the individual contrast agents. The interdependence of the blood density on the AP dimension of the patients was also studied due to its practical use and it was documented that there is a good correlation of the decreasing density with the AP dimension as a simple parameter used instead of finding out patients{\crq} weights.
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Evaluating new aromatic hop genotypes
Henychová, Alena ; Pulkrábek, Josef (advisor) ; Jaroslav, Jaroslav (referee)
Hop growers request new cultivar should have qualitative parameters of Saaz semi-early red-bine hop with higher yield potential. Therefore currently, there are efforts to breed new aroma cultivars.
The aim of diploma thesis was to evaluate and choose new breeding aroma genotypes, which would show equal or better quality and quantity parameters than Saaz semi-early red-bine hop registered cultivar, based on production indicators, chemical and genetic analyses. Obtained data were evaluated by basic statistical characteristics, two-sided t-tests for independent selections and correlation analysis.
A yield is the most important quantitative parameter, which is mainly and significantly dependent on climatic conditions. All evaluated genotypes in diploma thesis have reached higher average yields than ŽPČ cultivar, except genotype 4799. Genotype 4801 reached the highest theoretical yield (2.2 tons of dry hops) in year 2014 and genotype 4975 (1.77 tons of dry hops) in year 2015 from achieved results.
A content of alpha bitter acids is the most important qualitative parameter. All aroma new breeding lines have shown parameters of fine aroma hops according to chemical analyses of hop resins. Aroma genotype 4975 showed the highest average contents of alpha and beta bitter acids, balanced ratio between alpha and beta bitter acids, the lowest contents of cohumulone and colupulone, and as well it kept a low or middle variability in all studied traits of chemical analyses of hop resins. A relative content of farnesene higher than 12% is a typical for aroma hop cultivars with ŽPČ cultivar origin. All evaluated genotypes achieved this criteria.
We evaluated the relationship to Saaz semi-early red-bine hop cultivar based on genetic analyses. Genotype 4799 has been genetically the closest to ŽPČ.
Brewed beers have been a same quality as beers from Saaz semi-early red-bine hop cultivar by sensory evaluation.
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Effect of long term fertilization on behalf fraction of nitrogenous substances in fodder alfalfa
Matunová, Jana ; Hakl, Josef (advisor) ; Josef, Josef (referee)
The representation fraction of crude protein in forage legumes significantly influences nitrogen utilization by ruminants. Similar researches were not previously realized. The aim of this thesis is valorizing of long-term fertilization on vegetation structure and representation fraction of crude protein in forage alfalfa. Experimental measurements were carried out at the Research Institute of Crop Production in Prague, Ruzyne. The crop of alfalfa was in the context of long-term fertilization experiment established in the spring of 2013. An attempt with a sown variety Moravia is arranged in the scheme of split-plot. Samples were taken only from the first cut in 2015, each of one line of 50 cm in every block. In the experiment are evaluated four contrasting versions of fertilization (unfertilized control crop, growth fertilized by organic, by mineral and by combination both types of fertilizers). Each variant was repeated for three times. This thesis showed that long-term fertilization influences the parameters of the structure stands of alfalfa. We observed a greater proportion of L/m2 in fertilized variants, an also these stems were higher. Additionally, we observed higher profits, which were in correlation with the sinking share of representation leaves in the growth. Analysis showed that the behalf of nitrogenous substances and individual crude protein fractions is not constant, but is changeable during different variants of fertilization. Unfertilized crop contained on the average 221 g/kg dry matter of nitrogenous substances. The highest protein coken were at crops fertilized organically, 248 g/kg. In the control variant was detected on the average of 328 g/kg of fraction A. This fraction was most abundantly represented in growths with mineral fertilizers, 418 g/kg. On the contrary variant fertilized by combination had the lowest contents of fraction A, 307 g/kg. The highest concentration of B1 was found in mineral fertilized crops, 75 g/kg. For nitrogenous fraction B2 was detected the
highest concentration in crop fertilized by combination of mineral and organic fertilizers, 531 g/kg. For nitrogenous fraction B3 was found the highest concentrations in mineral-fertilized growths (NPK). This value is 24 g/kg. By nitrogenous fraction C was found highest concentration in control growth and crop fertilized with mineral, 80 g/kg. On the contrary, in crops fertilized organically was measured lowest value, 67 g/kg. We can conclude from the results, that the best profile fraction of crude protein has variant fertilized with a combined manner.
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Effect of internal factors on milk production and quality
Šťásek, Jan ; Toušová, Renata (advisor) ; Jan, Jan (referee)
The aim of this thesis was to monitor and evaluate the impact of internal factors on the production and quality of milk in a herd of montbeliarde cattle. The hypothesis was that worse results of reproduction adversely affect milk production. Data collection took place on a farm Osičky agricultural company Agrodružstvo Lhota pod Libčany for the period from 1.1.2010 to 31.12.2015. The file was obtained 1 849 standard lactations completed in this period. The source of data for evaluation of milk production, milk quality and reproductive performance of cows were cards, program Farmsoft from Farmtec used to herd management and output data from the inspections carried out by the utility Chovservis Inc. residing in Hradec Kralove.
A statistically highly significant difference (P<0,01) between the first and all other amounts lactation in milk, fat and protein kg per lactation and fat in % and between 1st and 5th and more lactations in % protein. Was a positive effect of length of service period and the length of the intervening period the quantity of milk, fat and protein in kg per lactation at significance level P<0,001 and the negative influence of the length meantime to protein content in % (P<0,001). He was also found at least P<0,001 positive effect on lactation length produced kilograms of milk, fat and protein. Fat and protein also positively influenced the amount of milked milk (P<0,001). It was statistically insignificant effect on the incidence of mastitis production and milk quality (P>0,05), based on correlations may have an adverse effect on the percentage of fat and protein at a higher incidence of mastitis expected. The influence of the proportion of blood Montbeliarde breed was statistically proven only on the amount of milk and protein in kg per lactation, but still pure-bred animals came out the best in all of the indicators except for milk production fat percentage.
From comparison of the calving showed that his herd performance increases every year, the quality of milk as the fat content in % but conversely decreases. For the month of calving has been shown to influence the percentage of fat and protein at a significance level of P<0,001, the quantity of milked milk (P<0,01) and the amount of produced protein in kg per lactation (P<0,05).
The hypothesis that impaired reproduction results negatively affecting milk production has not been confirmed. It was found to influence reproduction indicators on production and quality of milk, but this influence in a positive direction. The negative effect was demonstrated only for the length of the interim influence on protein content in %.
Overall, the level of flock assessed as very good, but there are many indicators of production and reproduction that is necessary with respect to the potential of improving the breed.
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May the creation of a fund center help to increase a country's competitiveness?
Kubínová, Pavla ; Rybáček, Václav (advisor) ; Urban, Luděk (referee)
A high concentration of automotive industry in the Czech economy and its dependence on exports to Germany could be compared to a poorly diversified investment portfolio. At the time when the manual-labor-intensive industries move to countries with a lower labor costs and even stable German economy is losing pace of growth, it is necessary to consider how to support the competitiveness of the Czech economy and ensure sustainable economic growth. The work deals with the question whether a greater focus on the financial sector and with a strong collective investment market may be a possible solution. Author seeks to find the answer thru analysis of this industry and its impact on the domestic economy of the countries with the largest collective investment fund market. The analysis did not prove the initial assumption that the intensive development of the collective investment market in the country will significantly help to grow HPD. However, given the strong correlation between the volume of assets under management and HPD some kind of connection cannot be excluded. A multiplying effect on the other industries is only average, on the other hand the analysis of the competitiveness indicators showed the strength of the industry.
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The Use of Psalms in Pastoral Care
Matulíková, Magda ; Filipi, Pavel (advisor) ; Sláma, Petr (referee)
This work aims to explore the possibility of using the biblical book of Psalms in pastoral counseling. Doing so, it wants to be synthesis of the Church's tradition, from the beginning recognizing the healing potential of Psalms, a new perspective on the correlation of the Old Testament Exegesis science and experience, and some impulses from the theory of pastoral care. Powered by TCPDF (www.tcpdf.org)
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Analysis of the effects and risks of the ricochet projectiles of charge gun
Juříček, Ludvík ; Moravanský, Norbert ; Rekeň, Viktor
The authors analyse the ricochet bullet effect on biological model of swine leg. The experiment simulates the real professional Slovak police action using the ammunition of 9 mm (type 82) in the municipal city zones. The results reveal the high ricochet bullet wound potential. The numeric model of the ballistics simulation points out the theory of the ricochet bullet terminal effect and the correlation of the terminal effects and the distance between ballistic barrier and wounded person. The evaluation of conclusions contribute to understanding the ricochet bullet wound effects and the principles of special forces ammunition selection for use in municipal city zones with lower risk of the other person gunshot injury.
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Ground-level ozone - seasons, relationships, conjunctions
Borovanský, Jan
Ground-level ozone - seasons, relationships, conjunctions Jan Borovanský Abstract Episodes of increased ground-level ozone concentrations change with the environment. While in urban areas are the increased concentrations irregular and remain short in the ground-level of atmosphere, in the background environment and higher altitude areas they last longer with very low amplitude. From the urban areas to background areas increase annual mean concentration of ground-level ozone as well. Ground-level ozone is secondary pollutant - its concentration depends on amount of precursors in the atmosphere and on meteorological conditions. Dependence on ozone precursors is changing progressively with the type of environment while meterological conditions play relatively same role in all types of environment. In urban areas, relation to ozone precursors is quite strong, in contrast with background areas where no significant relation is registered (the same correlation can be observed with increasing altitude). Therefore a distant transmission is considered as the dominant source of ground-level ozone in the background areas. Relationships between ground-level ozone and its precursors within the scope of daily regime are further studied in this work. Resulting curve in a chart has octal shape and can be divided into 4 main...
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Study of the antimicrobial effects of selected spices
Kalábová, Jana ; RNDr.Eva Dvořáčková (referee) ; Voběrková, Stanislava (advisor)
The antimicrobial effects of cinnamon, clove and ginger (grand and fresh) extracts against Bacillus subtilis, Aspergillus niger and Pichia fermentans were studied in this thesis. Selected spices were extracted in three solvents (ethanol, water and ethyl acetate) and inhibition effect on tested microorganisms was studied using two methods disc diffusion and broth dilution methods. The antioxidant activity and total polyphenolic compounds from spices were also determined. The results showed that cinnamon and clove extracts in ethyl acetate and ethanol were a promising antimicrobial substances for all tested microorganisms. Combination of cinnamon and clove especially ethyl acetate extracts showed an aditive effect. However, in the case of broth dilution method, fresh ginger inhibited bacterial growth under optimal growth conditions of Bacillus subtilis (35 °C, pH 7, 250 rpm). Minimum inhibitory concentration (MIC) values for all susceptible microorganisms was determined 8,3 mg/ml. The highest amounts of polyphenolic substances were found in cinnamon and clove ethanol extract and this result was in correlation with antioxidant activity.
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