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Evaluation of ontogenetic development of the mandible using geometric morphometric methods
Kiebelová, Alena ; Velemínská, Jana (advisor) ; Brůžek, Jaroslav (referee)
During ontogeny there are a lot of changes in the entire human skeleton. This thesis deals with shape changes in the mandible, which are caused by genetic, hormonal, as well as mechanical factors. The most important mechanical factors influencing the shape of mandible are development of deciduous and permanent dentition and also development of masticatory muscles. 34 children mandibles of known age and 14 adult mandibles were analysed and compared for this thesis. Data were obtained by scanning coordinates of 36 landmarks using Microscribe G2X, and then were processed by software PAST and Morphologika2 using multivariate statistics (PCA, MANOVA). Geometric morphometrics is used for a detailed analysis of shape changes of the mandible. There is no difference between dental and chronological age. In conclusion, lower jaw narrows during growth, the body extends more in the region of third molars and the ramus grows mainly in the region of condylar process. Chin prominence also occurs during ontogeny. In the group of adult mandibles the variability is caused by coronoid process height and the body width. The hypothesis, that age groups are significantly different from each other, and therefore due to tooth mineralization there are marked shape changes, is confirmed.
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Morphology of the mandible with regard to the demographic structure of the early medieval burial area Mikulčice
Thon, Tomáš ; Bejdová, Šárka (advisor) ; Velemínský, Petr (referee)
This Master's thesis focuses on the influence of socioeconomic status on the morphology of the mandible of individuals from the early medieval burial area in Mikulčice. This hillfort was an important center of power of the Great Moravian Empire with a stratified society. This work compares 2 different approaches on how to divide the inhabitants. The first of them is the division of individuals according to the location of graves into individuals from the castle, sub-castle, and hinterland. The second approach is the division of individuals according to the richness of grave equipment into individuals with rich and poor grave equipment. A different social status is associated mainly with different diets. Therefore, the attachments of the masticatory muscles are the most affected areas. A total of 132 individuals (59 males and 73 females) were analyzed. The material was evaluated by methods of geometric morphometrics. The used methods were CDP DCA, GPA, two-sample t-test, PCA, MANOVA, and SVM. Sexual dimorphism was observed in all sub-groups of the Mikulčice population. Men have larger mandibles with rami wider apart. The biggest differences are between individuals from the castle, the smallest between individuals with rich grave equipment. The distribution of individuals based on the location of...
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Morphology of the mandible with regard to the demographic structure of the early medieval burial area Mikulčice
Thon, Tomáš ; Bejdová, Šárka (advisor) ; Velemínský, Petr (referee)
This Master's thesis focuses on the influence of socioeconomic status on the morphology of the mandible of individuals from the early medieval burial area in Mikulčice. This hillfort was an important center of power of the Great Moravian Empire with a stratified society. This work compares 2 different approaches on how to divide the inhabitants. The first of them is the division of individuals according to the location of graves into individuals from the castle, sub-castle, and hinterland. The second approach is the division of individuals according to the richness of grave equipment into individuals with rich and poor grave equipment. A different social status is associated mainly with different diets. Therefore, the attachments of the masticatory muscles are the most affected areas. A total of 132 individuals (59 males and 73 females) were analyzed. The material was evaluated by methods of geometric morphometrics. The used methods were CDP DCA, GPA, two-sample t-test, PCA, MANOVA, and SVM. Sexual dimorphism was observed in all sub-groups of the Mikulčice population. Men have larger mandibles with rami wider apart. The biggest differences are between individuals from the castle, the smallest between individuals with rich grave equipment. The distribution of individuals based on the location of...
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Stress-Strain Analysis of Total Endoprosthesis of Temporomandibular Joint
Horňas, Jan ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
The presented master’s thesis deals with the problem of the application of total endoprosthesis (TEP) during temporomandibular joint (TMJ) replacement. The implantation of TEP occurs due the severe TMJ disease (arthrosis, ankylosis, cancer) or its macrotrauma. Condylar prosthesis is fixed during the implantation by self-tapping screws to the mandible. This fixation causes a change of stress-strain behaviour of mandible, TEP and fixation screws. In the thesis is performed the stress-strain analysis by using computational modeling in use the finite element method (FEM). Analysis is performed for six different screws positions (the number of screws is unchanged) and for a variable the static friction coefficient (in range 0.1 to 0.11) between condylar prosthesis (CP) and fossa prosthesis (FP). Altogether, 36 variants of computational models were created. The stress strain analysis detected a substantial influence of the static friction coefficient value to final results of displacements, contact pressure on the articulation surface between the CP and the FP and also to von Mises stress of the CP. A substantial influence of different screws position is detected for von Mises stress in the screws and for von Mises strain in the cortical and spongious bone tissue.
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Stress-Strain Analysis of Mandible with Fixator
Semerák, Jaroslav ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This diploma thesis deals with fixation of the lower jaw fractures using commercially produced fixators. The topic was researched on the basis of the available literature. The thesis also indicates basic anatomy of the surveyed area and nowadays the most commonly used materials. Subsequently, the stress-strain analysis of the lower jaw with the applied angular stable fixation plate was performed. The solution was performed for the lower jaw with a fracture in the area of the condyle with different types of fixation plates made of CP-Ti Grade 4. In addition, the strain analysis of the healed lower jaw with the fixators after the defect in the area of chin and angle was performed. The mechanical interaction analysis of the lower jaw with defect and applied fixation plate was solved by using computational modeling with variational approach, in use of the finite element method in Ansys Workbench 18.1. The thesis also describes in detail the creation of a computational model of the system and the subsequent solution.
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Origin and Biological Affinity of the Alleged Gravettian Mandible Předmostí 30.
Drahošová, Michala ; Brůžek, Jaroslav (advisor) ; Velemínský, Petr (referee)
Dissertation solves the problem of the origin of the mandible from collection of Moravian Museum in Brno. Publications of authors working in the location Předmostí u Přerova since the year 1884 have been used to achieve this goal. Simultaneously records in the incremental books of MZM in Brno have been researched, unfortunately without success. Therefore research of the biological affinity of the mandible P30 with others gravettiens discovery has been accepted as well as variability of recent humans. For study we used methods of geometric morphometrics, which allows us better clarify shape discrepancies in comparison with standard analytic methods. Comparison of shape variability of the mandible we used 91 cranial CT exposures of the recent Czech population. We placed 42 landmarks to segmented 3D models of the mandible and we made a PCA analysis. To extend the argument for justifiability to incorporate studied sample among discoveries from Předmostí u Přerova we created file of linear proportions of the tooth crown based on available publications and our own measuring. Morphological study, shape analysis of the mandible and dimension of the teeth leads us to results that the mandible P30 in our study can really belong to the Gravettien Age. Key words: Mandible, Molars, Předmostí u Přerova,...
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Stress-strain analysis of mandible with applied fixator due to the missing bone tissue
Fňukal, Jan ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This thesis deals with the fixation of lower jaw with bone tissue defect using commercially produced fixator. Large defects of bone tissue are mainly caused due to the removal of bone tissue affected by tumor. These topics have been researched on the basis of the literature. Subsequently, stress strain analysis of the lower jaw with the applied fixation plate was performed. This analysis was solved by using computational modeling with variational approach, ie the finite element method. The work also describes in detail the procedure of creating model of geometry, model of material, model of boundary conditions and loads with subsequent solution of several computational models. The stress strain analysis was done for lower jaw with varying size of the removed bone tissue with applied reconstruction plate made of CP-Ti Grade 4 and for the lower jaw with the plate, which is made of -Ti-Mo. Finally, the influence of the mechanical properties of the callus during formation of new bone tissue (callus healing) on the stress and deformation of the solved system was evaluated.
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Evaluation of ontogenetic development of the mandible using geometric morphometric methods
Kiebelová, Alena ; Velemínská, Jana (advisor) ; Brůžek, Jaroslav (referee)
During ontogeny there are a lot of changes in the entire human skeleton. This thesis deals with shape changes in the mandible, which are caused by genetic, hormonal, as well as mechanical factors. The most important mechanical factors influencing the shape of mandible are development of deciduous and permanent dentition and also development of masticatory muscles. 34 children mandibles of known age and 14 adult mandibles were analysed and compared for this thesis. Data were obtained by scanning coordinates of 36 landmarks using Microscribe G2X, and then were processed by software PAST and Morphologika2 using multivariate statistics (PCA, MANOVA). Geometric morphometrics is used for a detailed analysis of shape changes of the mandible. There is no difference between dental and chronological age. In conclusion, lower jaw narrows during growth, the body extends more in the region of third molars and the ramus grows mainly in the region of condylar process. Chin prominence also occurs during ontogeny. In the group of adult mandibles the variability is caused by coronoid process height and the body width. The hypothesis, that age groups are significantly different from each other, and therefore due to tooth mineralization there are marked shape changes, is confirmed.
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Biomechanical Studies of Facial Bone
Valášek, Jiří ; Janíček, Přemysl (referee) ; Horyl, Petr (referee) ; Florian, Zdeněk (advisor)
Presented work deals with Biomechanical study of the facial skeleton. This work is focused on the fixation of the mandible after removal of a tumor from affected bone tissue. The aim of the work is to perform biomechanical study of the facial skeleton with subsequent detailed stress strain analysis of two mandible implants designed and manufactured for specific patients. The geometry model of mandible used for design of mandible implants and used for computational modelling has been obtained on the basis of CT data of two patients. A Theoretical-Clinical sub-study that deals with the comparison the CT data processing which is necessary for creating the model of geometry is a part of the thesis. Two models of mandible with applied mandible implant have been created for two specific patients with tumorous mandible bone tissue. Stress strain analysis has been performed for these two models. Results of the stress strain analysis of two models of mandibles with mandible implants are presented in the final chapters of the thesis. Findings of the biomechanical study have been published and applied in clinical practice.
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Biomechanical studies of facial bone
Valášek, Jiří ; Florian, Zdeněk (advisor)
Presented work deals with Biomechanical study of the facial skeleton. This work is focused on the fixation of the mandible after removal of a tumor from affected bone tissue. The aim of the work is to perform biomechanical study of the facial skeleton with subsequent detailed stress strain analysis of two mandible implants designed and manufactured for specific patients. The geometry model of mandible used for design of mandible implants and used for computational modelling has been obtained on the basis of CT data of two patients. A Theoretical-Clinical sub-study that deals with the comparison the CT data processing which is necessary for creating the model of geometry is a part of the thesis. Two models of mandible with applied mandible implant have been created for two specific patients with tumorous mandible bone tissue. Stress strain analysis has been performed for these two models. Results of the stress strain analysis of two models of mandibles with mandible implants are presented in the final chapters of the thesis. Findings of the biomechanical study have been published and applied in clinical practice.
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