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Precise drug targeting using electromagnetic fields
Matějka, Alexandr ; Vyroubal, Petr (referee) ; Mačák, Martin (advisor)
The present bachelor thesis deals with the study of electromagnetic fields used for precise drug targeting from the point of view of numerical simulations. This area is very interesting from different points of view. The use of numerical simulations is currently a very attractive, but not widely used solution. In this bachelor thesis, a numerical model is developed to model the phenomena under investigation. Furthermore, the effect of the proximity of the magnetic field source on the targeting efficiency of drug carriers was analyzed in this thesis. The use of simulations of the presented issue can help to streamline and accelerate the application of the stated methods in practical applications.
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Compressible fluid motion in time dependent domains
Sýkora, Petr ; Feireisl, Eduard (advisor) ; Pokorný, Milan (referee)
In this work we study the existence of weak solutions for compressible Navier-Stokes equations in unbounded time dependent domains. Using the methods introduced in Feireisl E. Dynamics of Viscous Compressible Fluids we extend the results of article Feireisl E. Neustupa J. Stebel J., Convergence of a Brinkman-type penalization for compressible fluid flows, which studies the flow with a "no-slip" boundary condition on bounded domains. Next, we extend results of article Feireisl E. Kreml O. Nečasová Š. Neustupa J. Stebel J., Weak solutions to the barotropic Navier- Stokes system with slip boundary conditions in time dependent domains, which studies flow with compete Navier boundary condition. Finally, we discuss solutions for rotating fluid system. In this case, there are new members in momentum equation, representing the Coriolis and centrifugal force, which cause problems.
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Numerical simulation of compressible flows with the aid of multigrid methods
Živčák, Andrej ; Dolejší, Vít (advisor) ; Knobloch, Petr (referee)
We deal with the numerical solution of the Navier-Stokes equations describing a motion of viscous compressible flows. The governing equations are discretized with the aid of discontinuous Galerkin finite element method which is based on a discontinuous piecewise polynomial approximation. The discretizations leads to a large nonlinear algebraic system. In order to solve this system efficiently, we develop the so-called p-multigrid solution strategy which employ as a projec- tion and a restriction operators the L2 -projection in the spaces of polynomial functions on each element separately. The p-multigrid technique is studied, deve- loped and implemented in the code ADGFEM. The computational performance of the method is presented.
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Analysis of unsteady flows of incompressible heat-conducting rate-type viscoelastic fluids with stress-diffusion
Bathory, Michal ; Bulíček, Miroslav (advisor) ; Feireisl, Eduard (referee) ; Süli, Endré (referee)
We prove a global-in-time and large-data existence of a suitable weak solution to a system of partial differential equations describing an unsteady flow of homogeneous incom- pressible viscoelastic rate-type fluid. The material parameters are continuous functions of temperature and, in particular, the dependence of the shear modulus is assumed to be linear. It is shown that studied models obey the fundamental laws of thermodynamics. The key step towards the existence proof is derivation of the balance of entropy. This in- equality is paramount in the analysis and as its consequence, we obtain sufficient a priori estimates, positivity of temperature and also regularity of the elastic deformation. The second part of the thesis deals with the existence analysis for the isothermal case, however using a completely different method, which is of independent interest. 1
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Fluid Simulation Using GPU
Frank, Igor ; Chlubna, Tomáš (referee) ; Milet, Tomáš (advisor)
This thesis focuses on fluid simulation, particularly on coupling between particle based simulation and grid based simulation and thus modeling evaporation. Mentioned coupling is based on the article Evaporation and Condensation of SPH-based Fluids of authors Hendrik Hochstetter a Andreas Kolb. The goal of this thesis is not purely implementing ideas of the mentioned article, but also study of different methods used for fluid simulation.
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Numerical solution of flows in time dependent domains with elastic walls
Hadrava, Martin
Title: Numerical solution of flows in time dependent domains with elastic walls Author: Martin Hadrava Department: Department of Numerical Mathematics Supervisor: prof. RNDr. Miloslav Feistauer, DrSc., dr. h. c. Supervisor's e-mail address: feist@karlin.mff.cuni.cz Abstract: This work is devoted to the numerical solution of flow in time dependent domains with elastic walls. This problem has several applications in engineering and medicine. The flow is described by the system of Navier-Stokes equations supplemented with suitable initial and boundary conditions. A part of the boundary of the region oc- cupied by the fluid is represented by an elastic wall, whose deformation is described by a hyperbolic partial differential equation with initial and boundary conditions. Its right- hand side represents the force by which the fluid flow acts on the elastic wall. The goal of this work is to elaborate a numerical method for solving this coupled problem based on the finite element method and the ALE formulation of the equations describing flow. A for- mulation and analysis of the problem together with discretization, algorithmisation and programming of modules, which were added to an existing software package, is presented. The method that was worked out is applied to solve test problems. Keywords: interaction of flow and an...
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Analysis of unsteady flows of incompressible heat-conducting rate-type viscoelastic fluids with stress-diffusion
Bathory, Michal ; Bulíček, Miroslav (advisor)
We prove a global-in-time and large-data existence of a suitable weak solution to a system of partial differential equations describing an unsteady flow of homogeneous incom- pressible viscoelastic rate-type fluid. The material parameters are continuous functions of temperature and, in particular, the dependence of the shear modulus is assumed to be linear. It is shown that studied models obey the fundamental laws of thermodynamics. The key step towards the existence proof is derivation of the balance of entropy. This in- equality is paramount in the analysis and as its consequence, we obtain sufficient a priori estimates, positivity of temperature and also regularity of the elastic deformation. The second part of the thesis deals with the existence analysis for the isothermal case, however using a completely different method, which is of independent interest. 1
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Interaction of flow and an elastic body
Kosík, Adam
In the submitted work we are concerned with the numerical simulation of fluid flow and elastic body interaction. This is a coupled problem of the equations of two kinds, equations describing the flow and equations describing dynamical behaviour of the elas- tic body, which is partly surrounded by the fluid. These systems are coupled by suitable transmission conditions. The fluid flow is described by the Navier-Stokes equations, which are reformulated by the ALE method because of the deformation of the computational domain caused by the body movement. The deformation of the elastic body is described by the linear elasticity system with the generalized Hooke's law. We solve the problem by the finite element method. The developed methods are tested on the physical model of human vocal folds. 1
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Analysis of unsteady flows of incompressible heat-conducting rate-type viscoelastic fluids with stress-diffusion
Bathory, Michal ; Bulíček, Miroslav (advisor)
We prove a global-in-time and large-data existence of a suitable weak solution to a system of partial differential equations describing an unsteady flow of homogeneous incom- pressible viscoelastic rate-type fluid. The material parameters are continuous functions of temperature and, in particular, the dependence of the shear modulus is assumed to be linear. It is shown that studied models obey the fundamental laws of thermodynamics. The key step towards the existence proof is derivation of the balance of entropy. This in- equality is paramount in the analysis and as its consequence, we obtain sufficient a priori estimates, positivity of temperature and also regularity of the elastic deformation. The second part of the thesis deals with the existence analysis for the isothermal case, however using a completely different method, which is of independent interest. 1
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Analysis of unsteady flows of incompressible heat-conducting rate-type viscoelastic fluids with stress-diffusion
Bathory, Michal ; Bulíček, Miroslav (advisor) ; Feireisl, Eduard (referee) ; Süli, Endré (referee)
We prove a global-in-time and large-data existence of a suitable weak solution to a system of partial differential equations describing an unsteady flow of homogeneous incom- pressible viscoelastic rate-type fluid. The material parameters are continuous functions of temperature and, in particular, the dependence of the shear modulus is assumed to be linear. It is shown that studied models obey the fundamental laws of thermodynamics. The key step towards the existence proof is derivation of the balance of entropy. This in- equality is paramount in the analysis and as its consequence, we obtain sufficient a priori estimates, positivity of temperature and also regularity of the elastic deformation. The second part of the thesis deals with the existence analysis for the isothermal case, however using a completely different method, which is of independent interest. 1
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