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Process optimalization and lean implementation in the manufacturing company Tyco Electronics Czech Ltd
Rudolf, Jiří ; Štroner, Marek (referee) ; Strejček, Jan (advisor)
This diploma thesis is focused on the optimization of a specific process in the environment of the manufacturing company that supplies the components in the automotive and other industries. The theoretical part explains the principles and techniques of optimization of production processes and describes the placement of workplaces. The practical part of thesis analyzes the current state of the production process, identifies potential for improvements and proposes a new layout of workplaces. The project is then evaluated from both technical and economical viewpoint.
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Vliv polynenasycených mastných kyselin n-3 na expresi vybraného genu u modelového organizmu
Strouhalová, Eliška
The aim of my thesis was to assess the influence of polyunsaturated fatty acids n 3 (DHA and EPA) on gene expression, mainly PPARy, in model organism. The expression of PPARy gene is increased by these polyunsaturated fatty acids and thus they decrease the risk of development of inflammation and atherosclerosis. This hypothesis was tested on 40 test rats (Wistar albino). The first 7 weeks the rats were fed with a diet containing beef tallow and sweet condensed milk until they manifested mild obesity and inflammation. During other 7 weeks they were divided into 4 groups, each containing 10 individuals. One of the groups was further fed with diet containing beef tallow (control group), other groups received diet with 6% content of oil from safflower added, 6% content of fish oil (high content of EPA) or 6% content of oil from Schizochytrium alga (high content of DHA). The expression of PPARy was measured by using molecular-biology methods at the end of the trial. It was proven that the diet rich on DHA increases PPARy gene expression (P<0,05). The increase of PPARy gene expression in a diet containing fish oil was inconclusive (P>0,05). With these results we confirmed the hypothesis that diet rich on PUFA n3 decreases the risk of inflammation development and atherosclerosis and that DHA is significantly more effective.
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Vliv polynenasycených mastných kyselin n-3 na markery zánětu u modelového organizmu
Pešková, Petra
The aim of this thesis was to verify the hypothesis implying that n-3 polyunsaturated fatty acids inhibit the development of mild chronic inflammation. The experiment was conducted on rats with different diets (control, with the addition of safflower oils, fish oils and oils from algae Schizochytrium). For processing the results of the collected tissues was used determination of expression of selected genes by qRT-PCR, detection of proteins and in the cytosol and nuclear fractions by Western blot and the quantification of cytokines by ELISA. Feeding oil from algae Schizochytrium has led to lowering the final weight and blood glucose, further to enhance expression of PPAR-gama and increasing the production of anti-inflammatory cytokines IL-10 and TGF-beta1. In kontrast, no difference was observed in the expression of GPR120 and adiponectin receptors or proteins in an amount of NF-kappaB and PPAR-gama between diets. Elevated plasma levels of adiponectin were found. The results of the experiment shows that it is possible to recommend oil from algae Schizochytrium as a useful supplement of human diet as prevention of chronic degenerative diseases.
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The lipid quality of our economically significant fish species
KREJSA, Jakub
The level of fish consumption in the Czech Republic is very low. One of the possible factors influencing this situation is low awareness of the customer or consumer. The thesis "The Lipid Quality of our economically significant fish species" works with the list of nineteen economically most significant fish species not only including fish from the semi-intensive and intensive breeding, but also such species that are interesting for the consumption from the sport fishing point of view. The samples taken from particular fish were primarily used for the analysis of the fat content and fatty acid composition. The analysis established very interesting results in this field and created basis for further analysis for establishing atherogenic and thrombogenic index or for formation of nutritive values mentioned as "Big 7" (fat content and the ratio of fatty acid out of it, sacharide content and the sugar ratio in it, protein content, ash content and energy value) by particular fish species according to the regulation ES 1169/2011. The results of this work confirmed that the fat content and its composition are highly influenced by the type of ingested nourishment. The fish bred in semi-intensive way with the highest fat content are Common carp (7,62 ? 2,9 %) and Silver carp (6,87 ? 1,37 %). On the contrary the predatory fish evinced the fat content usually within 1%. The fish from extensive breeding or the types caught in sport fishing are in the fat con-tent more balanced. The fattest fish in this group is Silver Bream (5,52 ? 0,44 %) and the lowest content evinced Goldfish (1,14 ? 0,38 %). Also the species living in the aquaculture and living in the free waters as well were compared (Common carp, Rainbow trout, Peled, Tench, Wels catfish). The fatty acid composition significantly depends on the fat content. The predatory fish contain 195 - 219 mg×100 g-1, the most (p0,05) was found by the peled from the extensive breed (1048 mg×100 g-1 EPA + DHA). The participation of SFA by the most of the fish was under 30%, the content of MUFA was the highest by the Common carp (52,71 ? 7,75 %), the lowest by the European perch (18,83 ? 1,12 %). Pike, Zander and European perch contain relatively the most of PUFA, this is over 50%. All the fish species (Nile tilapia excluded) show in this study the values of atherogenic index below 0,5 and thrombogenic index below 0,4. The total energetic value was counted from the results of nutritional values presented in the "Big 7" list. The higher energetic value is directly proportional to the increasing fat content. The fish species included in this thesis show the total energetic value in the range of 500 - 900 kJ×100 g-1. The results of this study bring complete, laboratory proven information about the nutrition composition of our fish. This data can be appli-cable not only to increase the knowledge of the customers but mainly to be used by breeders and manufacturers of fish as an implement of fulfilling the duty of stating the nutrition facts on their products according to ES 1169/2011 on the providing infor-mation about the eatables to the consumers.
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Ovlivnění plazmatické hladiny cholesterolu modelového organizmu polynenasycenými mastnými kyselinami n-3
Čeganová, Markéta
The aim of this thesis is to assess the influence of the polyunsaturated fatty acids, especially DHA and EPA in the diet on the animal organism in accordance to the levels of total HDL and LDL cholesterol and triglycerides in plasma. As experimental animals were used rats and they were divided into 3 groups of 10 pieces: control group with the addition of 6 % Carthamus tinctorius (n-6 flares), the group with the addition of 6 % fish oil (n-3: EPA, DHA fish) and the group with 6 % addition of oil from Schizochytrium (n-3: DHA, DHA). After 40 days the animals were putted to death according to relevant regulations. Blood lipids were obtained from blood samples by spectrophotometry. Value of polyunsaturated fatty acids of n-3 and n-6 was set by gas chromatography in the liver, muscle and adipose tissue. In accordance to the increase of content n-3 PUFA in group with fish oil and with oil from Schizochytrium, total and LDL cholesterol was reduced in comparison of samples in control group. In comparison to the control group were TAG reduced only in the group with addition of oil.
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Comparison of Export Support Systems in Austria and the Czech Republic
Zbranková, Lenka ; Král, Petr (advisor) ; Vokáč, Matěj (referee)
This master's thesis deals with the comparison of export support systems in the Czech Republic and Austria. In the first chapter, the terms "export support" and "export credit agencies" are defined and instruments of export supporting policies as well as their positive and negative aspects are listed and EU regulation and policies in this field are briefly described. A short description of the Czech Republic and Austria follows. Special attention is paid to the following analysis of export strategies and export credit agencies in both economies. This descriptive theoretical part is complemented by a practical case study carried out in cooperation with TOSHULIN, a.s. -- a successful producer and exporter of machinery. Both systems of export support are evaluated from the point of view of the company's sales department. The thesis concludes with an evaluation of the topic, a comparison of the effectiveness of both export support systems, and the author's suggestions for potential innovation and improvement in this area.
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Effect of alternative feed on content of omega 3 fatty acids in fish muscles
KREJSA, Jakub
The aim of my bachelor thesis was to evaluate the effect of fish oil substitution for rapeseed oil in the feed on the fat content and fatty acid composition in the flesh of Brook trout (Salvelinus fontinalis) in the finishing feeding technology. The experiment was conducted in 2012 for the period of 135 days. The individuals of Brook trout were divided into four groups. The first two groups were fed with the feed containing only rapeseed or fish oil. The feeding of the remaining two groups was divided into two phases. In the first phase the fish oil was partly replaced by the rapeseed oil. In the second phase the fish oil was replaced by the feed which contained fish oil only. It was proved that a half replacement of the fish oil with the rapeseed oil does not influence the content of fat in the flesh of Brook trout. We observed that the fish had the higher content of MUFA and n-6 PUFA and lower content of n-3 PUFA, DHA, EPA and n-3/n-6 with increasing period where the feed with rapeseed oil was served. Following application of the finishing feeding technology with the use of feed with fish oil had the opposite effects. Furthermore, the dilution model was proved to be highly reliable for the prediction of the fatty acids composition. Based on these findings, it is possible to predict changes of fatty acid composition in the flesh of Brook trout as well as to predict how long is needed to apply finishing feeding to reach required content of EPA+DHA or n-3 HUFA.
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Japan's approach to regionalism: Economic partnership agreements
Wagnerová, Markéta ; Hnát, Pavel (advisor) ; Krč, Jakub (referee)
This work contains general characteristics of bilateralism as a new element of regionalism. Because Japan is the typical representative of bilateralism, this work aims at the approach of this country to regionalism, bilateralism and at list of Japan's bilateral agreements. The work describes especially factors which influenced the Japan's approach to regionalism, the way how Japan applies bilateralism and the content of its bilateral agreements. In the last part is described the first japan's bilateral agreement: Japan-Singapore economic partnership agreement.
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