|
|
Synthesis of foamed bioceramics for potential medical applications
Doboš, Petr ; Šoukal, František (oponent) ; Palou, Martin (vedoucí práce)
The main aims of the diploma work were focused on the preparation of porous hydroxyapatite ceramics for potential biomedical applications. Hydroxyapatite slurries were synthesized by sol-gel and precipitation method. Then, the slurries were dried and calcinated at 1000 °C for phase control. These samples of HAP were analyzed by SEM, FTIR, and XRD. To prepare apatite porous ceramics, the slurries were foamed by polymeric sponge method and direct foaming method including (polymeric expancel and glass bubbles). The sintering temperature was established after 1000 °C by sponge method and 1200 °C by direct foaming. The microstructure measurement by SEM and structure analysis by MIP of both porous hydroxyaptite indicates the regular porosity including macro, meso and micropores with different pore size distribution. The average size of pores prepared by sponge method is found between 1-5 µm with mono-dispersed porosity. The total porosity is 63.5 % with the total surface area 3.048 1 m/g. Porous hydroxyapatite prepared from expancel showed a poly-dispersed porosity with three main areas: 50–100 µm, 5–10 µm and the third one in range 0.5–1 µm, respectively. The total porosity is 67.6 % with total surface area 19.090 3 m/g. The bioactivity of both was tested in SBF for 7 days. It was found that in precipitation method was observed non-compact bioactive layer. The results were measered by SEM analysis.
|
|
|
Příprava biokeramických materiálů pro medicínské aplikace
Doboš, Petr ; Šoukal, František (oponent) ; Palou, Martin (vedoucí práce)
Cílem práce bylo připravit vzorky práškového hydroxyapatitu pomocí sol-gel a precipitační metody. Po syntéze byly prášky vylisovány a vypáleny při teplotách 500 °C, 800 °C a 1100 °C. Vzorky HAP byly podrobeny analýze FTIR, XRD, SEM. Výsledné měření poukazuje na velikost HAP částic v rozmezí mikro až nano rozměrů. Průměrná velikost dominantních zrn je v oblasti kolem 5 – 8 µm pokryté menšími částicemi o rozměru 1 µm. Byla sledována mikrostruktura materiálu a bioaktivita in vitro v simulovaném krevním roztoku po 4 týdnech. Bioaktivita byla ovlivněna teplotou výpalu, od které závisí mikrostruktura. Je zřejmé, že tloušťka vrstvy hydroxyapatitu na povrchu roste s teplotou výpalu.
|
|
|
Synthesis of foamed bioceramics for potential medical applications
Doboš, Petr ; Šoukal, František (oponent) ; Palou, Martin (vedoucí práce)
The main aims of the diploma work were focused on the preparation of porous hydroxyapatite ceramics for potential biomedical applications. Hydroxyapatite slurries were synthesized by sol-gel and precipitation method. Then, the slurries were dried and calcinated at 1000 °C for phase control. These samples of HAP were analyzed by SEM, FTIR, and XRD. To prepare apatite porous ceramics, the slurries were foamed by polymeric sponge method and direct foaming method including (polymeric expancel and glass bubbles). The sintering temperature was established after 1000 °C by sponge method and 1200 °C by direct foaming. The microstructure measurement by SEM and structure analysis by MIP of both porous hydroxyaptite indicates the regular porosity including macro, meso and micropores with different pore size distribution. The average size of pores prepared by sponge method is found between 1-5 µm with mono-dispersed porosity. The total porosity is 63.5 % with the total surface area 3.048 1 m/g. Porous hydroxyapatite prepared from expancel showed a poly-dispersed porosity with three main areas: 50–100 µm, 5–10 µm and the third one in range 0.5–1 µm, respectively. The total porosity is 67.6 % with total surface area 19.090 3 m/g. The bioactivity of both was tested in SBF for 7 days. It was found that in precipitation method was observed non-compact bioactive layer. The results were measered by SEM analysis.
|
|
|
Příprava biokeramických materiálů pro medicínské aplikace
Doboš, Petr ; Šoukal, František (oponent) ; Palou, Martin (vedoucí práce)
Cílem práce bylo připravit vzorky práškového hydroxyapatitu pomocí sol-gel a precipitační metody. Po syntéze byly prášky vylisovány a vypáleny při teplotách 500 °C, 800 °C a 1100 °C. Vzorky HAP byly podrobeny analýze FTIR, XRD, SEM. Výsledné měření poukazuje na velikost HAP částic v rozmezí mikro až nano rozměrů. Průměrná velikost dominantních zrn je v oblasti kolem 5 – 8 µm pokryté menšími částicemi o rozměru 1 µm. Byla sledována mikrostruktura materiálu a bioaktivita in vitro v simulovaném krevním roztoku po 4 týdnech. Bioaktivita byla ovlivněna teplotou výpalu, od které závisí mikrostruktura. Je zřejmé, že tloušťka vrstvy hydroxyapatitu na povrchu roste s teplotou výpalu.
|
host ::
RSS.