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Diagnosis of students' difficulties in didactic tests in CLIL.
Šturcová, Alena ; Novotná, Jarmila (advisor) ; Koldová, Helena (referee) ; Semanišinová, Ingrid (referee)
DISERTAČNÍ PRÁCE Diagnostika obtíží žáků v didaktických testech při výuce CLILem Diagnosis of students' difficulties in didactic tests in CLIL Mgr. Ing. Alena Šturcová ABSTRACT IN ENGLISH The dissertation deals with diagnosing students' difficulties in didactic tests in CLIL (Content and Language Integrated Learning) integrating mathematics and English. The aim of the thesis was to design and analyze didactic tests that are suitable tools for identifying sources of difficulties in CLIL teaching, where mathematics and English are integrated, and to determine whether it is possible to analyze students' results in individual tasks in these tests to determine whether the student has difficulties with mathematics or English. The thesis also addresses the attitude of CLIL students and CLIL teachers of a specific Czech school to CLIL teaching and learning. The thesis is divided into six chapters. The first chapter summarizes the theoretical background of the CLIL method, the next two chapters focus on assessment in general and assessment in CLIL, including some research on CLIL assessment. The fourth chapter is partly theoretical and partly practical, describing experiences and original research related to lesson planning, teaching goals, and CLIL implementation. The fifth chapter focuses on assessment of teaching...
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The changes in cell adhesion molecule expression in various pathological states in animal models
Koldová, Helena ; Nachtigal, Petr (advisor) ; Kopecký, Martin (referee)
The changes in cell adhesion molecule expression in various pathological states in animal models. Mgr.Helena Koldová This rigorous work was focused on the study of atorvastatin effects in apoE/LDL- receptor deficient mice. The aim was to elucidate whether atrovastatin posses similar effects that are common in humans. Female ApoE/LDL receptor-double-knockout mice at 8 weeks of age were randomly divided into 2 groups. The control group of animals (n=8) was fed with the atherogenic (western type) diet for another 8 weeks. The same atherogenic diet and treatment period was used in other two groups where atorvastatin was added to the diet at the dosage of 10 mg/kg per day. Biochemical analysis of blood cholesterol fractions, ELISA analysis of monocyte chemoattractant protein-1, vascular cell adhesion molecule-1 levels in blood, and stereological analysis of atherosclerotic plaque size in aortic sinus was performed. The biochemical analysis showed that administration of 10 mg/kg of atorvastatin resulted in a mild decrease of blood cholesterol fractions. Moreover atorvastatin significantly increased the HDL levels. This mild positive influence on lipid parameters was accompanied by moderate anti-inflammatory effect which was manifested by a reduced level of MCP-1 in blood. In conclusion apoE/LDL-receptor deficient...
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The changes in cell adhesion molecule expression in various pathological states in animal models
Koldová, Helena ; Nachtigal, Petr (advisor) ; Kopecký, Martin (referee)
The changes in cell adhesion molecule expression in various pathological states in animal models. Mgr.Helena Koldová This rigorous work was focused on the study of atorvastatin effects in apoE/LDL- receptor deficient mice. The aim was to elucidate whether atrovastatin posses similar effects that are common in humans. Female ApoE/LDL receptor-double-knockout mice at 8 weeks of age were randomly divided into 2 groups. The control group of animals (n=8) was fed with the atherogenic (western type) diet for another 8 weeks. The same atherogenic diet and treatment period was used in other two groups where atorvastatin was added to the diet at the dosage of 10 mg/kg per day. Biochemical analysis of blood cholesterol fractions, ELISA analysis of monocyte chemoattractant protein-1, vascular cell adhesion molecule-1 levels in blood, and stereological analysis of atherosclerotic plaque size in aortic sinus was performed. The biochemical analysis showed that administration of 10 mg/kg of atorvastatin resulted in a mild decrease of blood cholesterol fractions. Moreover atorvastatin significantly increased the HDL levels. This mild positive influence on lipid parameters was accompanied by moderate anti-inflammatory effect which was manifested by a reduced level of MCP-1 in blood. In conclusion apoE/LDL-receptor deficient...
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