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Possibilities of using of Vitis vinifera as a source of raw materials for cosmetic production
Hanáková, Pavlína ; Vítová, Eva (referee) ; Zemanová, Jana (advisor)
This bachelor thesis deals with preparation of extraction from various parts of grapevine and their consequent use in the manufacture of cosmetics. The theoretical part is focused on general characteristics of grapevine, its taxonomic classification, occurrence and cultivation. Subsequently, the chemical composition of grapevine parts and their uses in cosmetic, food and pharmaceutical industries is described. The final part is devoted to particular types of extractions and methods of determinativ of total phenolic substances. The experimental part deals with the optimization of the prepared extract in order to obtain the extract with the highest amount of total phenolic substances with respect to production costs. Factors such as selection of the appropriate solvent and extraction time are examined. 50% ethanol at the room temperature was found to be an optimal solvent. Finally, the physical and chemical properties, such as density, pH and refractive index were determined for the purpose of producing a material safety data sheet. The extract was processed into cosmetic products.
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Folic acid release from branched and crosslinked oligoester carriers
Hanáková, Pavlína ; Dittrich, Milan (advisor) ; Šnejdrová, Eva (referee)
ABSTRACT-EN In the thesis were demonstrated possibilities for modification of the release period for folic acid incorporated into matrices prepared from poly(DL-lactic acid) branched by mannit or dipentaerythritol. The range of release process duration from two days to 45 days was demonstrated. Process was shortened by increasing concentration of triethylcitrate used as plasticizer of oligoester carrier, the second possibility concentration of branching agent builded into molecule, and the third one was pH of dissolution medium. Prolongation of release of folic acid was achieved by crosslinking agent as additive incorporated into matrices.
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Possibilities of using of Vitis vinifera as a source of raw materials for cosmetic production
Hanáková, Pavlína ; Vítová, Eva (referee) ; Zemanová, Jana (advisor)
This bachelor thesis deals with preparation of extraction from various parts of grapevine and their consequent use in the manufacture of cosmetics. The theoretical part is focused on general characteristics of grapevine, its taxonomic classification, occurrence and cultivation. Subsequently, the chemical composition of grapevine parts and their uses in cosmetic, food and pharmaceutical industries is described. The final part is devoted to particular types of extractions and methods of determinativ of total phenolic substances. The experimental part deals with the optimization of the prepared extract in order to obtain the extract with the highest amount of total phenolic substances with respect to production costs. Factors such as selection of the appropriate solvent and extraction time are examined. 50% ethanol at the room temperature was found to be an optimal solvent. Finally, the physical and chemical properties, such as density, pH and refractive index were determined for the purpose of producing a material safety data sheet. The extract was processed into cosmetic products.
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Folic acid release from branched and crosslinked oligoester carriers
Hanáková, Pavlína ; Dittrich, Milan (advisor) ; Šnejdrová, Eva (referee)
ABSTRACT-EN In the thesis were demonstrated possibilities for modification of the release period for folic acid incorporated into matrices prepared from poly(DL-lactic acid) branched by mannit or dipentaerythritol. The range of release process duration from two days to 45 days was demonstrated. Process was shortened by increasing concentration of triethylcitrate used as plasticizer of oligoester carrier, the second possibility concentration of branching agent builded into molecule, and the third one was pH of dissolution medium. Prolongation of release of folic acid was achieved by crosslinking agent as additive incorporated into matrices.
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