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Mortality in high ages
Malá, Kateřina ; Mazurová, Lucie (advisor) ; Cipra, Tomáš (referee)
In this thesis, we study modelling of mortality in high ages by several approaches. Some of mentioned models take into account the phenomenon of mortality deceleration. Further, we present several ways of estimating of exposed to risk in (almost) extinct cohorts. We focus especially on the survivor ratio method but we also mention the MD method and the DG method. Finally, we perform a numerical study.
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Analysis of drug-related problems in outpatients II.
Sperottová, Šárka ; Doseděl, Martin (advisor) ; Malá, Kateřina (referee)
Analysis of drug-related problems in general practitioners office II. Author: Šárka Sperottová Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Background: A Drug-Related Problem - DRP - is according to Pharmaceutical Care Network Europe - PCNE - an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes. We can encounter DRP in every general practitioner's - GPs - office all around the world. But with proper cooperation between practitioners and pharmacists we could reduce the number of problems. That would be big benefit for patients and health system as well. This thesis is focused on anticoagulant drugs, mainly on DOAC group - direct oral anticoagulants - and their DRP in it's theoretical part. Practical part of thesis is analysis of DRP in GPs office itself. Aim: Theoretical part - describe the process of haemostasis and the possibilities of influencing this process by drugs. Discuss DRP of anticoagulants, especially oral anticoagulants and heparins. Practical part - identify and describe DRP. Sort them by PCNE Classification for DRP V5.01. Analyse and describe the most frequent drug-related problems occurring in general...
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Drug Information Centre service analysis II.
Čikovská, Natália ; Malá, Kateřina (advisor) ; Matoulková, Petra (referee)
Drug Information Centre service analysis II. Author: Natália Čikovská Supervisor: PharmDr. Kateřina Malá, Ph.D. Consultant: PharmDr. Petra Thomson Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Drug Information Centre (DIC) of the Faculty of Pharmacy in Hradec Kralové was established in 1994 and is the only university-based DIC in the Czech Republic. DIC is providing expert information about drugs, such as answering medicines-related enquiries received from healthcare professionals. Objective: The objective of diploma thesis was to gather and analyze information about the informational service of LIC FAF UK a FN HK in 1994-2016 aimed for general characteristics of drug enquiries and professional drug information resources used for solving the enquiries. Methods: Detailed analysis of DIC activities was performed to compile suitable data. All enquiries from years between 1994 and 2016 were summarized into a database using Microsoft Excel software. General characteristics of the enquiries were analyzed, such an average number of enquiries per year or time needed for resolving one enquiry. Information about enquirers was considered as well, e.g. their profession and region, from which the enquiries were sent....
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Attitudes and beliefs on HPV infection and vaccination II
Regnerová, Veronika ; Zimčíková, Eva (advisor) ; Malá, Kateřina (referee)
Attitudes and beliefs on HPV infection and vaccination II Veronika Regnerová, PharmDr. Eva Zimčíková, Ph.D. Background: Cervical cancer is the second most common type of cancer in women. The majority of cervical cancer cases are caused by human papillomavirus (HPV). Three vaccines have been approved to prevent HPV infection and related diseases. Objectives: The study aimed to analyse the knowledge and attitudes regarding HPV, cervical cancer and HPV vaccination in secondary school students in the Czech Republic. Methods: The study was carried out in May 2017 at four secondary schools. A questionnaire used for data collection comprised 15 items including questions on demographic characteristics, knowledge about cervical cancer and HPV, vaccination coverage, HPV perceived susceptibility and seriousness, and beliefs on HVP vaccination. Results: A total of 667 students participated (mean age: 16.8 y ± 1.18; 63% female); 20.5% were smokers, 24.7% God believers. Most of the students (97.0%) heard about cervical cancer and penile cancer, significant proportion (68.3%) knew HPV was the causative factor. Half of the respondents (49.9%) have heard about vaccination against HPV. Among cervical cancer risk factors HPV infection was reported in 58.1% cases followed by promiscuity (14.5%), irregular...
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Drug Information Centre service analysis I.
Chmelíková, Barbora ; Malá, Kateřina (advisor) ; Zimčíková, Eva (referee)
Drug Information Centre service analysis I. Author: Barbora Chmelíková Supervisor: PharmDr. Kateřina Malá, Ph.D. Consultant: PharmDr. Petra Thomson Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction and aim of the thesis This study deals with the analysis of enquiries of the Drug Information Centre (DIC) of Faculty of Pharmacy in Hradec Králové, Charles University and University Hospital Hradec Králové. DIC have a unique role within provide clinical- pharmaceutical care in the provision of drug information. The aim of this study was the analysis of drug enquiries in 1994-2016 focusing on their urgency, type of enquiries and ATC groups. Methods The data analysed were collected from all recorded enquiries in the Excel database within 1994-2016. Therefore, it was necessary to transform some of the paper- recorded enquiries from 1994 to 2002 into the Excel database in which the enquiries data from 2003 to 2016 were already included. Data analysis firstly focused on the characteristics of the enquiries (quantity, healthcare professionals' characteristics such as region, position, enquiry type and urgency of the enquiries). The character of enquiries included properties and active pharmaceutical ingredient of the medicines,...
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Optical measurement of liquid surface tension
Malá, Kateřina ; Pech, Ondřej (referee) ; Malý, Milan (advisor)
This bachelor thesis explores the topic of measuring surface tension of liquids. The theoretical section explains the basic principles as well as possibilities of application of several measuring methods. In the next part, the most suitable method is selected in terms of ease of use, accuracy and purchase cost. The pendent drop method has been found to fit these criteria. The experimental section of the thesis describes the measuring apparatus and the analytic tool used. The results comprise an analysis of the factors which may affect the measurement precision as well as a comparison of an automatic and a manual analysis, and a reference measurement that confirms the aperture as efficient at measuring surface tension of liquids.
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Attitudes towards treatment and knowledge of hormonal contraceptives among final year pharmacy students
Pavlíková, Veronika ; Malá, Kateřina (advisor) ; Pokladníková, Jitka (referee)
The attitudes toward the treatment and knowledge about hormonal contraception among the final year pharmacy students Author: Veronika Pavlíková¹ Supervisor: PharmDr. Kateřina Ládová, Ph.D.¹ Consultant: PharmDr. Anna Oleárová, Ph.D., MPHš ¹Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic šDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic Introduction: Hormonal contraception (HC) is ranked among the widespread birth control methods used in a broad age structure of women worldwide. Based on of the health status, lifestyle, user's preferences or non-contraceptive benefits, it is possible to choose from the wide spectrum of HC, which differs in dosage and composition. Aim: The aim of this thesis was to determine the attitudes toward the treatment and knowledge about the HC among the final-year pharmacy students upon the completion of the mandatory 6-month long practical training in the pharmacy and knowledge acquired during the studies. Methods: The on-line survey was the realized in students of faculties of pharmacy in the Czech Republic and in the Slovak Republic, who had already completed the mandatory 6-month long practical training or who have just been...
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Attitudes towards treatment and knowledge of hormonal contraceptive users
Fufaľová, Veronika ; Malá, Kateřina (advisor) ; Matoulková, Petra (referee)
Diplomová práca Postoje k liečbe a znalosti užívateliek hormonálnej antikoncepcie Abstract Attitudes towards treatment and knowledge of hormonal contraceptive users Author: Veronika Fufaľová¹ Supervisor: PharmDr. Kateřina Ládová, Ph.D.¹ Consultant: PharmDr. Anna Oleárová, PhD., MPHš ¹Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic šDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic Introduction: Hormonal contraception (HC) is popular and a reliable birth control method. Its use is although associated with some risks and many myths or misconceptions. Objective: The aim of this thesis was to determine the attitudes towards treatment and awareness of HC risks of its users in regard to various types and application forms in specific region by means of anonymous questionnaire. Methods: The research was carried out as a prospective questionnaire survey. Anonymous questionnaires consisted of 35 questions divided into 6 sections to obtain sociodemographic data, information concerning HC users and their form of HC, information about the extent of knowledge concerning gynaecological examination, HC risks and HC misconception awareness. One part of questionnaire was focused...
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Insurance pricing methods based on risk measures
Malá, Kateřina ; Branda, Martin (advisor) ; Mazurová, Lucie (referee)
In this thesis we study various risk measures and one of their characteristics - the coherence. We talk especially about value-at-risk (VaR in short), respectively about conditional value-at- risk (CVaR). We also mention the advantage of CVaR against VaR. After that we discuss the most common forms of compound distribution that are used in practice. The final part of this bachelor thesis is dedicated to a numerical study where we calculate mean, variance, VaR a CVaR for specific values of parameters.
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Body image and body dissatisfaction in nonclinical population
Malá, Kateřina ; Hrachovinová, Tamara (advisor) ; Jelínek, Jakub (referee)
The work deals with the theme of body image and dissatisfaction over one's own body in nonclinical population. Theoretical part includes knowledge of physical self perception and it focuses mainly on the factors that have some affect on the body image. Body image is significantly influenced by the age, sex, personal traits and an affiliation to a social class. The work also points out, that high demands have been recently placed on the visual aspects and how much slenderness is being idealized and the ideal of beauty has been displayed in the media. This results in the dissatisfaction with one's own body that may bring about considerable health, psychological and finally partnership problems. Last but not least the work demonstrates the overview of body image measurement methods. In the empirical part is suggested a survey which main goal is more complex interpretation of physical self perception in the elderly. This part illustrates how important the appearance for the elderly really is and what determines their satisfaction or dissatisfaction with one's own body and how much this contentment is related with the life quality of the senior citizens in general.
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