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Influence of phenylketonuria on osteopenia
Tůmová, Linda ; Hučko, Boris (advisor) ; Adéla, Adéla (referee)
The Masters thesis deals with The influence of external factors on bone loss in patients with phenylketonuria. The phenylketonuria is relatively rare disease, but it is one of the most common inherited metabolic diseases, with the incidence of 1:10000 newborns in Europe. It is an autosomal recessive disease, caused by the deficiency or low activity of the enzyme phenylalanine hydroxylase in liver. This enzyme catalyzes the hydroxylation of phenylalanine to tyrosine in the presence of cofactor tetrahydrobiopterin. Mutations in the gene for this enzyme (previously described more than 800 mutations) or in the gene for the cofactor (2% of cases) results when received normal diet, a large amount of unprocessed phenylalanine can accumulate in the blood and other bodily fluids while the levels of tyrosine and its metabolites are low. This situation leads to severe mental retardation, eczema, microcephaly, growth retardation, physical disability, psychiatric problems, etc. Due to the fact that mental retardation is usually irreversible, testing and early diagnosis is crucial when it comes to this disease. Because of the severity of the disease, a mandatory screening test for newborns was implemented in the Czech Republic in 1975, followed by a treatment diet, that consists of a strict restriction of protein and supplementation of amino acid preparations without phenylalanin. One of the chronic problems connected to this illness are decreased bone density in children and adults with PKU. Although the underlying cause of osteopenia in phenylketonuria has not yet been elucidated, it is a consequence of several factors.
Using the questionnaire, my data was evaluated for the incidence of bone loss in patients with PKU. As my research shows, the incidence of osteoporosis in patients with PKU is higher than the normal population. In 41,3 % of PKU patients were diagnosed osteopenia and osteoporosis in 2,2 %. In the normal population, 99 % of respondents have a normal BMD, while 1 % were diagnosed the osteoporosis. Furthermore, comparing the data with the normal and PKU populations, it has not been confirmed by external influences such as BMI, drinking coffee and cola drinks, and physical activity for example, in regards to bone loss. Conversely showed, that phenylketonuriacs consume cola drinks more than the normal population, most likely due to the factor of gaining quick energy.
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Quality of life in rural municipalities - study comparing situation within and outside protected areas
TŮMOVÁ, Lenka
The topic of bachelor thesis was comparison of selected aspects quality of life in two villages, located in different conditions from aspect of protection of nature. Specifically is issuing about comparison of village Lomnice nad Lužnicí in PLA Třeboňsko and village Dolní Bukovsko (out of protected landscape area). Thesis has got character of empirical comparison study, combinated quantitative and qualitative accesses of data collecting and analysing. Results from questionnaire investigation are representing satisfaction of the population with quality of life in this locations.
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The advantage of building society in new legislative terms compared with mortgage loans
TŮMOVÁ, Lenka
The topic of this master thesis is to compare benefits from the building society account with the mortgage loan. The whole comparison will be done according to the new legislative. The aim of this study is to find whether it is more profitable to invest into your property with the mortgage or the building society account. For this collation eight different companies are approached. Four of them are building societies and four are banks. The experts from those companies were given three examples with different height of LTV from different applicants with different purposes. Those experts also assessed which indicators applicants should consider. According to these recommendations clients have ordered indicators by their assumed importance. Finally offers were evaluated by TOPSIS method and ordered by its advantageousness.
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Intensity of nursing work on the oncological department.
TŮMOVÁ, Lucie
This Bachelor thesis deals with working demands of nurses employed in oncology departments. Because of being in continuous contact with people (patients, their families or colleagues) nurses working in these departments should be empathetic, kind, patient and helpful. The theoretical part of this thesis focuses on general characteristics of oncological departments, description of nursing specifics, available oncological treatment, the role of nurses in palliative treatment and issues of burnout syndrom. The theoretical part presents the results of semi-structured interviews conducted with nurses working in oncology departments at "Ceské Budějovice Hospital" and "Na Bulovce Hospital". Based on the dialaogues were the case reports which later became the basis for category tables. The results show that nurses perceive their work as difficult, mostly from the psychological aspect. The oncology nurses have to face terminally ill people, dying and death on a daily basis. They are exposed to risks of cytostatic agents. They may often suffer from tiredness which can lead to disruption of social, physical and psychical wellfare and even to the burnout. Influenced by these factors the nurses often feel stressed and are not often familiar with how this stress can be prevented or tackled. A brochure based on the obtained information has therefore been compiled for nurses with the aim to inform them about these issues.
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System of payment and its development with focus on the current tendency
TŮMOVÁ, Lenka
The aims of bachelor´s thesis are to compare individual type of payments and to describe present condition system of payment in the Czech Republic. The theoretical part deals with legislation on system of payment, history of money and history of banking. The next chapter defines cash and cashless payment as well as payment systems. In the practical part of bachelor´s thesis principle the payment systems - CERTIS and TARGET - is cleared up. Then, the fees for payment in Czech banks are compared. The authoress chose the three biggest bank and the one newest bank in the Czech Republic for interesting contrast. Last part shows outcomes of questionary, where 162 respondents replied to 17 questions about system of payment. The questionary was prepared for this thesis and the answers are confront with annual reports of individual bank.
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Czech development aid
Tůmová, Lucie ; Ježek, Tomáš (advisor) ; Kundrotaite, Monika (referee)
The diploma thesis deals with the foreign development cooperation of the Czech Republic. It assesses previous trends of development cooperation analyzing concepts and tools in terms of bilateral assistance or commitments to international organizations. It reviews not only the public sector, but also non-profit organizations and private entities. The aim is to investigate to what extent the economic growth of countries is affected by development assistance and to what by developing countries themselves and if the Czech development aid has fundamentally contributed to the support of democracy, private enterprise, protection of private property and human rights. The part of the thesis is practical application on Serbia, one of the largest recipients of the Czech development cooperation in recent years. In conclusion the thesis evaluates current concepts and introduces solutions and recommendations for further development of the aid, both domestic or global scale.
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Internal environment of selected company and its evaluation
TŮMOVÁ, Lenka
In my graduation theses (it is a final project of engineering study at South Bohemia University, in field of commercial business) I focused on internal environment of the company called Centropen a.s. which is situated in Dačice. For evaluation of internal atmosphere I used a few different methods. One of them was the analysis of the results in particular functional fields, I mentioned Bostonian matrix shortly and SWOT analysis. As for an evaluation of functional fields I chose research and development, production, purchase, sale, marketing, human resources and financing. A separate chapter was given to marketing in which was made a questionnaire research, analyzing individual activity, which the company makes for own presentation in public. I focused on a concrete advertising campaign as well {--} The School Campaign. This campaign is every year the most extensive action which the Centropen company prepares together with fullservis advertising agency. Concerning evaluation of functional fields, as the weakest point showed up the field of human resources. The company doesn{\crq}t deal with searching and education new generation in this area at all even further education of current employees, nevertheless the significant part of workers higher and middle management are really close to retiring age. Marketing is able to keep up only thanks to an important help of the agency. Marketing on its own is able to cover just the area of propagation, not complete marketing. As for the SWOT analysis, where are mingled the diagnosis of the internal and external environment, I summarized competitive environment. It is more then clear, that competitive pressures increase and Centropen company, who{\crq}s still using success from previous years, a little bit fell asleep in fight with competition. The significant positive is a strong financial background without credit indebtedness, which helps to support power of the company.
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Analysis of the internal environment of a selected company
TŮMOVÁ, Lenka
I focused on the internal environment of company Centropen. When exploring this area I utilised several methods. They included setting up of the Boston Matrix, an analysis of sources and competences according to functional areas and a SWOT analysis. In order to obtain complete data for SWOT analysis, which partially merges the diagnostics of an internal and external environment, I briefly referred to the Porter´s model and described the market characteristics.
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Forms of money and how their emissions
Tůmová, Lenka ; Votava, Libor (advisor) ; Mašová, Miroslava (referee)
In this work, I describe the history of money, when, how and why it arose. Also, I will consider what the advantages and disadvantages of different forms of money. As the last chapter in the history of money I will bring the historical reasons for conversion to another currency. Next I will address the present. Present way of emissions and forms of money, mainly on the role of cash and non-cash money now and in the future. The last block of work will be devoted to transition to another currency. I'll look at what the Czech Republic should expect from the adoption of the euro and to recommend measures that should be taken to avoid subsequent problems such as inflation. In this chapter, I will work with the experience of other countries in the European Union, especially with experience in Slovakia.
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Iranian society, policy and economy in years 1980-1988
Tůmová, Lucie ; Tumis, Stanislav (advisor) ; Soukup, Jaromír (referee)
This work analyses social, political and mainly economic development of Iran in the 1980s. I will primarily focus on the Shi'ite Islam which controlled all the Iranian society at that time, headed by clerical leader ayatollah Ruhollah Khomeini. However, the most important event was the Iran-Iraq war which ruined the Iranian economy. This war influenced both Islamic Republic of Iran and The Middle East and its relationship with the West, particularly with the United States. So I will analyze the 1980s in Iran also in connection with foreign relations where the oil and the armament industry played an important role.
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