National Repository of Grey Literature 17 records found  previous11 - 17  jump to record: Search took 0.01 seconds. 
Activation of the protein kinase B and glycogen synthase kinase-3 signalling pathway during transient differentiation of human colon cancer HT-29 cells
Tuháčková, Zdena ; Šloncová, Eva ; Hlaváček, Jan ; Sovová, Vlasta ; Velek, Jiří
Using synthetic peptides which reproduce phosphoacceptor sites in the molecule of GSK-3, PKB an eIF2B, we found that phosphorylation and activity of PKB increased very early during in vitro differentiation induced by sodium butyrate. This was inhibited by wortmannin, the selective inhibitor of phosphoinositol-3 kinase, indicating that the control of PI3 kinase/PKB/GSK-3 signalling pathway is the early event of transient differentiation of the human colon cancer cells HT-29.
The Application of the Elimination voltammetry in the Study of Phytochelatine Complexes with Zinc
Šestáková, Ivana ; Navrátil, Tomáš ; Velek, Jiří
For two synthetically prepared phytochelatins – PC2 and PC3 - the formation of complexes with zinc ions was studied in borate buffer pH 8.5, using DC and DP voltammetry on HMDE. In both cases, in addition to complexation, oxidation of peptide takes place. Elimination voltammetry with linear scan could distinguish particular Zn-complexes and showed their reduction at adsorbed state and the influence of kinetics -slow formation or labile behaviour of complexes.
Antibodies against receptors coupled with G-proteins
Hýblová, D. ; Veselský, Leopold ; Velek, Jiří ; Železná, Blanka
Two antibodies against angiotensin receptor AT2 prepared against two short sequences recognized the receptor on Western blots of several rat and mouse tissues where AT2 is expressed. Both antibodies recognized the identical proteins; they lost this property after immunoabsorption with their antigen peptides. With one antibody, we were able to immunoprecipitate the receptor.

National Repository of Grey Literature : 17 records found   previous11 - 17  jump to record:
See also: similar author names
2 VELEK, Jindřich
5 Velek, Jan
1 Velek, Josef
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