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The God's Eye View: Epistemic Ideal or Conformity with Standards of Justification?
Krejčová, Kateřina ; Švec, Ondřej (advisor) ; Ritter, Martin (referee)
(in English) In the Enlightenment liberation from the religious myth one can see a paradoxical shift that is characterized by the fact that the scientist in the new type of secularized culture takes over the role previously dedicated to the priest. She holds the position of a mediator between what is human and superhuman, subjective, imperfect and flawed and a distant truth to which human beings feel a specific kind of responsibility. As the "soft sciences" ceded territory to the exact sciences, it happened because we have not yet been able to give up the dream of a perfectly neutral God eye's view. The author wants to show that objectivity itself is not impartial, but that it is a name for different kinds of rationality, which are at different times considered to be epistemic virtues.
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Procedurally generated video games as a humanistic platform of the future
Salaba, Petr ; Miesenböck, Julia (advisor) ; Krejčová, Kateřina (referee)
An intermedia analysis of "art video games" in the perspective of humanistic values inspired by the theory of neorealism. Italian screenwriter and film theoretician Cesare Zavattini argues that a truly humanistic and socially conscious film would not be based on a dramatic plot, but that it would rather come from a factual depiction of every individual value inherent to the filmed topic. In my work, I propose that such a non-narrative approach can be well executed in the context on the new interactive media, concretely in video games that are based on procedurally generated environment rather than on a linear script.
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Preparation of tumour ligand B7-H6 with coiled-coil tag and verifying of its binding to receptor NKp30
Krejčová, Kateřina ; Vaněk, Ondřej (advisor) ; Moserová, Michaela (referee)
Natural killer cells (NK cells) are part of innate antitumor immunity. These cells have the capacity to prevent viral infection or malignant transformation without prior antigen sensitization. Activation of NK cells consist of different recognition strategies. Mechanism of activation is based on down-regulated expression of MHC gp I molecules on the cell surface. NK cells possess both activation and inhibitory receptors that transmit activation or inhibitory signals which determine if NK cells are activated or not, and thus whether the target cell will be lysed or spared. NKp30 is a type I transmembrane receptor which recognize the stress-induced cell surface ligand B7-H6. Interaction of these two proteins leads to the initiation of immune response. The main aim of this thesis is the preparation of cell ligand B7-H6 with coiled-coil peptide tag in human embryonic kidney cell lines HEK293 GnTI- and HEK293T. Successful preparation of B7-H6 with coiled-coil tag on its C-terminus was verified by mass spectrometry. Its interaction with natural cytotoxicity receptor NKp30 was also proven by sedimentation analysis. Key words: NK cells, recombinant expression, B7-H6, HEK293, coiled-coil (This thesis is written in Czech)
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Regimes of Rationality / Objectivity between Historical Epistemology and Pragmatism
Krejčová, Kateřina ; Švec, Ondřej (advisor) ; Ritter, Martin (referee)
(in English) The aim of the thesis is to introduce selected approaches to genealogy and changes of the concept of "objectivity". While historical epistemology puts this concept into a context of a particular historical period in which it was born and established itself, and therefore perceives "objectivity" as a novelty, pragmatism sees it as a relic of the discourse of Enlightenment and proposes to replace it with solidarity. Both approaches analyse difficulties of uncritical applications of this term in the history of philosophy and "avant la lettre" science and the assumption that objectivity is just a modification and another name of this concept which is a necessary condition of any knowledge. The thesis is based on texts of Lorraine Daston, Peter Galison, Richard Rorty, Thomas S. Kuhn and Perez Zagorin.
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Atmospheric characteristics of white dwarfs
Krejčová, Kateřina ; Kawka, Adéla (advisor) ; Mayer, Pavel (referee)
We have analyzed the ultraviolet spectra of 40 hydrogen-rich (DA) white dwarfs. These spectra have been obtained with the Far Ultraviolet Spectroscopic Explorer (FUSE) satellite and are publicly available via the MAST FUSE database. We derived the effective temperature and surface gravity by fitting the hydrogen Lyman spectral lines with model spectra. By applying white dwarf evolutionary models, we were able to determine the white dwarf mass, cooling age and absolute magnitude. These then allowed us to determine the distance to each star and its predicted gravitational redshift. We have identified several chemical elements in the white dwarf spectra. We determined the abundances of C, Si, P and S by measuring the equivalent widths of selected lines of these elements. Finally, we studied the spectra of J0623-376 and LM Com in more detail.
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The Electrical Enterprises of the City of Prague and Avant-garde Films
Krejčová, Kateřina ; PETŘÍČEK, Miroslav (advisor) ; VOJTĚCHOVSKÝ, Miloš (referee)
This paper, based on archival and period media research, tries to describe the relationship between the Electrical Enterprises of the City of Prague and the Czechoslovak avant-garde in the 1920's and 1930's. The Electrical Enterprises of the City of Prague helped to carry out several exceptional film and intermedia projects through their regular advertising contracts, including the film Praha v záři světel (Prague by Night, 1928), Zdeněk Pešánek's light-kinetic sculpture (1930) or the short experimental film Světlo proniká tmou (Light that Penetrates Darkness, 1931). There are also screenplays in the company archives which have never been realized but demonstrate much about the relationship between advertising and art in the interwar period. The author emphasizes the role of the public's general fascination with electrification, artificial light in the modern city and new forms in the collectively shared public space.
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Pojistné události v cestovním ruchu
Krejčová, Kateřina
This bachelor thesis deals with the issue of insurance in tourism. The theoretical part of the thesis describes the historical development of insurance, the basic legislation of contract of package tour and insurance contract according to the new civil code, and discusses the issue of travel insurance. The practical part analyses the specific risks in travel insurance. On the bases of questionnaire survey, given to travel agency's clients, is to investigate client's awareness in case of origin of individual insurance events. The main goal of this thesis is to create a manual for the clients of a particular travel agency which help them how to proceed in case of individual insured events.
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Analysis of Spanish in internet discussion forums
KREJČOVÁ, Kateřina
The diploma thesis folows up the analysis of the language of spanish speaking adolescents acros online discussion forums. The theoretic section mainly pursues the issues of the oral/written and colloquial/formal dichotomies which takes an important part in the resultant form of the language used on the internet. It also describes the general features of language, used on the internet, focusing spanish and adolescent users. The practical section analyses the graphic, morphosyntactical, semantic and pragmatic level of the language sample found on the internet discussion forums.
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