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Regulation of bacterial transcription by alternative sigma factors.
Benda, Martin ; Krásný, Libor (advisor) ; Roučová, Kristina (referee)
An important feature of bacteria is their ability to respond to various environmental conditions by regulation of transcription. This thesis is focused on regulation of transcription initiation by different sigma factors. Sigma factor is a specific subunit of RNA polymerase, which ensures correct recognition of promotor sequences. During exponential growth phase under ideal conditions, the cell transcribes most of the genes under the control of the so-called housekeeping sigma factor. In the transition to stationary phase, during sporulation or upon exposure to different stresses, many genes are activated and transcribed under the control of alternative sigma factors. This work presents a list of these alternative sigma factors of Bacillus subtilis, focusing on conditions under which the individual sigma factor is used, methods of activation and repression of these factors and on regulons controled by these sigma factors.
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Technological process of the end flow part
Benda, Martin ; Sedlák, Josef (referee) ; Píška, Miroslav (advisor)
The aim of this work is to create the technological process for the manufacturing the end flow part in EXCALIBUR ARMY spol. s r.o. The first part of the thesis focuses on structural and technological analysis of the component part. In the second part, two different production technologies are proposed. One on conventional machines and the another on the CNC turning center. At the end of work. The production times for these procedures are calculated, followed by a technical-economical evaluation in which the two proposed processes are compared.
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Potential and Limits of Nordic Cooperation
Benda, Martin ; Jireš, Jan (advisor) ; Slačálek, Ondřej (referee)
The master thesis searches for the core and character of the Nordic cooperation, especially in the perspective of actorness in international relations. It analyses the geopolitics of Norden and tries to project future development. Constructivist concepts of regional security complexes and brands in international relations is being used in the paper. It concludes that European integration is both the limit and potential of Norden. Nordic model looses its former exclusivity but at the same time it nordicizes a wider region.
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System approach to the Students' Union of the University of Economics in Prague
Kočí, Jakub ; Sigmund, Tomáš (advisor) ; Benda, Martin (referee)
The aim of this diploma thesis is the preparation and foundation of the Students' Union of the University of Economics in Prague, which is done by Soft systems methodology. In order to achieve this aim, the thesis elaborates a theory of student organizations and student unions in the Czech Republic. It also compares a set of rules governing student organizations at chosen Czech universities with chosen foreign universities. The result of this comparison is that chosen foreign universities have more systematic policies towards their student organizations. The research part of this thesis contains Analysis two (social) and Analysis three (political) from the Soft systems methodology. The results of the research contains defined set of roles, norms, values and a distribution of power in the environment of student organizations at University of Economics. Practical part of the thesis brings two complete learning cycles of the Soft systems methodology including root definitions, CATWOE and models of purposeful activity. Based on these two learning cycles, the thesis defines the general limits of Soft system methodology for the foundation of student union at Czech universities.
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Problematika návykový látek u žáků středních škol
Benda, Martin
Abstract This thesis deals with the awareness of high school students about substance abuse and the risks associated with the abuse of these substances. In the theoretical part I will try to map the situation regarding the current state of drug use in high schools. I will mention a few reasons why high school students with substance use begin and what dangers may bring such use. Readers will get to know terms such as drug addiction and what brings risks. Next, I will briefly describe addictive substances and specific effects of addictive substances among high school students. The end of the theoretical part will be devoted to primary prevention, minimal preventive programs in high schools, a description of school prevention education and prevention strategies. The practical part of the thesis is devoted to the detection of an anonymous questionnaire, which was presented to pupils at selected high school (vocational schools and high schools, SČMSD Znojmo). The research includes a survey with students of the first and third year of apprenticeship. The results of the survey are processed into tables and graphs, and then further discussed. The aim of the survey is to find out how high school pupils are familiar with the risks that drug use can bring and what is the role of these substances in the lives of adolescents. The results can also serve as supplemental information for school counselors, school prevention for at pursued school.
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