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The Analysis of Selected Factors that Influence the Pharmacotherapy of Diabetes Mellitus
Hendrychová, Tereza ; Šmahelová, Alena (advisor) ; Macek, Karel (referee) ; Svačina, Štěpán (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate Mgr. Tereza Hendrychová Supervisor Doc. MUDr. Alena Šmahelová, Ph.D. Title of Doctoral Thesis The analysis of selected factors that influence the pharmacotherapy of diabetes mellitus Introduction: Diabetes mellitus (DM) requires continuing health care as prevention of the rise of acute complications and lowering the risk of development and further progression of chronic complications. The choice of the treatment method is fundamental for reaching the therapeutic aims. That is why medical staff members should continuously monitor information about new possibilities of the therapy including the current ones which are still continuously specified. The management of diabetes mellitus requires the active approach of patient as well as the complex medical health care. The emphasis should also be placed on his/her adherence or attitudes and on the motivation to the treatment. Search part Aim: The aim of the search part was to analyze the possibilities of DM type 1 pharmacotherapy with the focus on the comparison of the treatment of CSII (continuous subcutaneous insulin infusion) and MDI (multiple daily injections) in adult diabetics with DM type 1 and the possibility of use of some...
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Importance of Metformin in the Treatment of Type 2 Diabetes Mellitus
Kučerová, Andrea ; Vlček, Jiří (advisor) ; Šmahelová, Alena (referee)
Importance of metformin in the treatment of type 2 diabetes mellitus Mgr. Andrea Kučerová, Department of Social and Clinical Pharmacy, Pharmaceutical Faculty in Hradec Králové, doctorate thesis, 2010 Metformin is biquanid which, during its therapeutic use, has undergone a period of perdition and fall followed by again rising up to the imaginary pharmacological-therapeutic summit when it became a "gold standard" in the treatment of patients with type 2 diabetes mellitus. Currently, it is recommended by the professional authorities abroad and in the Czech Republic as a first choice drug after determination of diagnosis together with diet and physical exercise. How these recommendations follow and reflect the diabetological prescription situation? What prevents the physicians-prescriptors from implementation of the recommendations into their daily practice? The aim and subject of this thesis is the issue of therapy of type 2 diabetes mellitus (DM) by means of oral antidiabetics (PADs) with a special focus on the decision mechanisms of selected prescription groups of physicians. A historical development of metformin must be reminded in the theoretical part of this thesis in order to better understand and substantiate these prescription habits, and furthermore a development and changes of its position in...
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Education of the diabetics in the area of selfmonitoring
Petříčková, Lenka ; Machalová, Iva (advisor) ; Schneiderová, Michaela (referee) ; Šmahelová, Alena (referee)
96 Annotation Author: Lenka Petříčková Organisation: Institute of Social Medicine, Charles University - Faculty of Medicine in Hradec Králové Name of the thesis: Education of Diabetics in the Area of Selfmonitoring Supervisor: Mgr. Machalová Iva, prim. MUDr. Jiří Veselý Number of pages: 125 Number of annexes: 10 Year of defence: 2010 Key words: education, diabetes mellitus, selfmonitoring of diabetes, glucose blood, glycaemic haemoglobin Bachelor thesis is about education of diabetics in the area of selfmonitoring. Theoretical part of this thesis is oriented on education which is essential part of treatment and on the meaning of education, goals, phases, form, resources of education, organisation and contents. This part further demonstrates dilemma of selfmonitoring that is selfmonitoring of glucose blood, glycaemic haemoglobin, selfmonitoring of ketonuria and glycosuria, weight and blood pressure monitoring. An emphasis of this thesis consist in a quantitative research investigation of knowledge in the area of selfmonitoring of glycaemia by diabetics in Broumov - Regional hospital of Náchod. Diabetics were separated into two age groups: 20-59 years and 60 years and more. Resulting information should be due to education similar in both groups of diabetics. Outcome of this thesis is proposal of educational...
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Pharmacotherapy analysis of diabetes mellitus in diabetologic consulting room.
Buriánková, Lenka ; Vlček, Jiří (advisor) ; Šmahelová, Alena (referee)
PHARMACOTHERAPY ANALYSIS OF DIABETES MELLITUS IN DIABETOLOGIC CONSULTING ROOM Student: Buriankova L. Tutor: Vlcek J., Dept. of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague,Czech Republic Background: Diabetes mellitus type 2 is a group of metabolic diseases whose common trait is hyperglycaemia. Aim: To assess the group of patients, diabetics with type 2 diabetes mellitus according to different points of view and to assess their treatment. Methods: 106 patients with DM type 2 (49 male, 57 female, mean age 61,8) were retrospectively studied for 23 months. The data were obtained from patient's data in diabetologic consulting room. Results: The concentrations of glycosylated haemoglobin were in 45 % of patients less than 6,5, 13 % of patients had these concentrations 6,5-7,5 and this can be considered as satisfying state of disease. 42 % respondents had higher concentrations of glycosylated haemoglobin. The most common medication in monotherapy were sulfonylureas in 25 % of patients and metformin in 16 % of patients. The most common combination of antidiabetics were metformin with sulfonylureas in 17 % and metformin with insulin in 12 % of patients. Insulin therapy was indicated in 39 % of patients (25 % in combination with oral antidiabetics, 14 % in...
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Monitoring of Evolution of Artistic Expressing a Family in a Pre-school Child´s Drawing
ŠMAHELOVÁ, Alena
A bachelor thesis deals with observing various ways of the family concept in drawings of pre-school children. Based on specialized literature, the theoretic part defines following terms: a pre-school period, an importance of a family, a drawing development, a drawing of a family. It characterizes a child in pre-school age from the motoric, cognitive, social, emotional, moral development and game point of view. It outlines family changes, relationships among family members and the importance of a family. It introduces the development and characteristics of an infant drawing and aims at the interpretation of a drawing of a family. The practic part using 20 children as a sample recognizes how the age and individual distinctions of a child affect the drawings of a family. Due to the drawing of a family and a dialogue, it reveals how a child is able to perceive a family and to illustrate it.
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