National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Cyclic and acyclic phosphonate tyrosine ester prodrugs of acyclic nucleoside phosphonates
Williams, M. ; Krylov, I. S. ; Zakharova, V. M. ; Serpi, M. ; Peterson, L. W. ; Krečmerová, Marcela ; Kashemirov, B. A. ; McKenna, Ch. E.
A series of P-O ester derivatives of HPMPA, HPMPC, PMEA a (R)-PMPDAP was synthesized as potential anti-malarial prodrugs.
New strategies in synthesis of acyclic nucleoside phosphonate prodrugs
Krečmerová, Marcela ; Tichý, Tomáš ; Blažek, Jiří ; Pomeisl, Karel
New syntheses of acyclic nucleoside phosphonate prodrugs including dioxolenone derivatives, functionalized alkoxyalkyl esters, utilization of hexafluorophosphate coupling agents and enzymatic glycosylations were described. Comparison of antiviral activities of diverse prodrugs was performed.

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