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Design of Accelerator for Oncological Therapy
Zbořil, Jan ; Siebert, Petr (referee) ; John, David (advisor)
The aim of this diploma thesis is the design of linear accelerator for oncology treatment. The design focuses on the improvement of the aesthethical side of the accelator, but also comes up with inventional solutions how to improve the radiation treatment of oncology patients to higher the chances of successful treatment of cancer.
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Solar Gains in Buildings
Tenora, Tomáš ; Uher, Pavel (referee) ; Rubinová, Olga (advisor)
Master’s thesis deals with solar gains in buildings. The thesis presents an overview of the theoretical knowledge to solve solar gain. The thesis deals possibilities of measuring the intensity of solar radiation and evaluation of data from the meteorological station in the experimental part. Application of topic is then used for polyfunctional building. This part aims to show possibilities of design of air conditioning systems for the purpose of making indoor microclimate and their subsequent evaluation.
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Object shape reconstruction based on the max(t,0)-pulse response
Doležal, Tomáš ; Dědková, Jarmila (referee) ; Štumpf, Martin (advisor)
This diploma thesis deals with a spatial imaging of targets using time-domain radar responses on the max(t,0) pulse. The problem is formulated for both perfectly electrically conductive and dielectric objects. The main aim of the thesis includes a code implementation calculating the profile functions of an unknown object from the mentioned time responses and a code for the subsequent reconstruction of an object in the MATLAB environment. A graphical user interface was created for testing purposes. The 3D probability function technique was used for the final reconstruction. The implemented technique achieves interesting results, which are presented in the final part of this thesis.
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Norway spruce chloroplast ultrastructure - heterogeneity within a needle.
Glanc, Natália ; Lhotáková, Zuzana (advisor) ; Kutík, Jaromír (referee)
6 Abstract Temperate forests serve as long term carbon storage and are affected by increasing carbon dioxide (CO2) concentration in the atmosphere. Norway spruce (Picea abies (L.) Karst.) is the most abundant conifer in the forests of the Czech Republic, therefore I studied the response of its photosynthetic aparatus to elevated CO2 concentration. The aim of my thesis was to analyze the impact of CO2 concentration on chloroplast ultrastructure in both shaded and exposed needles, focusing on the volume density of starch in the median cross-sections of mesophyll cell chloroplasts. The next aim of the study was to test whether the chloroplasts of the first subepidermal layer of mesophyll are representative for the whole needle with respect to starch volume density. The study was performed on eleven years-old Norway spruce trees that had been exposed to ambient or elevated concentration of CO2 for six years; the experiment had been carried out at the Bílý Kříž experimental station in the Beskids Mountains in cultivation chambers with automatically adjustable windows. First year needles of trees grown under abient (382-395ppm) or elevated (700 ppm) CO2 concentration were collected in October 2011. The needles were used to prepare ultrathin sections and the images of median chloroplast cross-sections were...
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PNF technique after arthroscopic stabilization of the shoulder
Benešová, Martina ; Holubářová, Jiřina (advisor) ; Pavlů, Dagmar (referee)
Title: PNF technique after arthroscopic stabilization of the shoulder joint Objectives: The objective of this work is to consider the possibility of use of the proprioceptive neuromuscular facilitation technique (PNF) in early stages of rehabilitation after arthroscopic stabilization of the shoulder joint. The idea is to use the phenomen of irradiation with which this concept works. Methods: The pilot experimental group consisted of 7 healthy participants with simulated arthroscopic stabilization of the left shoulder joint. The electromyography was used to record the electric activity of musculus trapezius pars descendens, pars transversa et pars ascendens, musculus deltoideus pars acromialis, musculus infraspinatus and musculus pectoralis major pars sternocostalis on the immobilized left arm; while using the PNF technique on the peripheral parts of the immobilised arm; and on the contra lateral arm. A 5s sequence of stabilised isometric contraction was analysed and all data further normalised to Maximal Voluntary Contraction (MVC). Considering the literature the 20% increase above the MVC was defined as substantial to assure sufficient functional capacity of the muscle fibres and therefore sufficient to stop muscle atrophy during immobilisation of the arm. Results: Results of this study support...
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Design and synthesis of surface architectures on fluorescent nanodiamonds
Havlík, Jan
anks to their unique properties and high biocompatibilities, fluorescent nanodiamonds are promising representatives of modern carbon nanomaterials with a broad range of applications. Nevertheless, their wider use is limited because of weak fluorescence intensity and low colloidal stability in the biological environment. e optimization of treatment procedures and development of new suitable surface designs is therefore critically needed. In this study, several key steps for fluorescent nanodiamond treatment have been optimized, leading to both a substantial increase in fluorescence intensity and to significantly lower surface damage caused by graphitization. Further, a new high-throughput irradiation technique was developed. e influence of surface chemistry on the fluorescence parameters was studied using partial fluorination of the functional groups on the nanodiamond surface. A novel method which significantly affects the interaction of nanodiamonds with biological systems by increasing of the homogeneity and circularity was developed. e potential of nanodiamonds for future medical and biological research was demonstrated on particles with complex surface architectures that enabled targeting and therapy of tumor cells. Moreover, a strong and highly selective affinity of fibroblast growth factors to diamond...
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Object shape reconstruction based on the max(t,0)-pulse response
Doležal, Tomáš ; Dědková, Jarmila (referee) ; Štumpf, Martin (advisor)
This diploma thesis deals with a spatial imaging of targets using time-domain radar responses on the max(t,0) pulse. The problem is formulated for both perfectly electrically conductive and dielectric objects. The main aim of the thesis includes a code implementation calculating the profile functions of an unknown object from the mentioned time responses and a code for the subsequent reconstruction of an object in the MATLAB environment. A graphical user interface was created for testing purposes. The 3D probability function technique was used for the final reconstruction. The implemented technique achieves interesting results, which are presented in the final part of this thesis.
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Design and synthesis of surface architectures on fluorescent nanodiamonds
Havlík, Jan
anks to their unique properties and high biocompatibilities, fluorescent nanodiamonds are promising representatives of modern carbon nanomaterials with a broad range of applications. Nevertheless, their wider use is limited because of weak fluorescence intensity and low colloidal stability in the biological environment. e optimization of treatment procedures and development of new suitable surface designs is therefore critically needed. In this study, several key steps for fluorescent nanodiamond treatment have been optimized, leading to both a substantial increase in fluorescence intensity and to significantly lower surface damage caused by graphitization. Further, a new high-throughput irradiation technique was developed. e influence of surface chemistry on the fluorescence parameters was studied using partial fluorination of the functional groups on the nanodiamond surface. A novel method which significantly affects the interaction of nanodiamonds with biological systems by increasing of the homogeneity and circularity was developed. e potential of nanodiamonds for future medical and biological research was demonstrated on particles with complex surface architectures that enabled targeting and therapy of tumor cells. Moreover, a strong and highly selective affinity of fibroblast growth factors to diamond...
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Design of Accelerator for Oncological Therapy
Zbořil, Jan ; Siebert, Petr (referee) ; John, David (advisor)
The aim of this diploma thesis is the design of linear accelerator for oncology treatment. The design focuses on the improvement of the aesthethical side of the accelator, but also comes up with inventional solutions how to improve the radiation treatment of oncology patients to higher the chances of successful treatment of cancer.
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Design and synthesis of surface architectures on fluorescent nanodiamonds
Havlík, Jan ; Kotek, Jan (advisor) ; Lang, Kamil (referee) ; Štěpánek, František (referee)
anks to their unique properties and high biocompatibilities, fluorescent nanodiamonds are promising representatives of modern carbon nanomaterials with a broad range of applications. Nevertheless, their wider use is limited because of weak fluorescence intensity and low colloidal stability in the biological environment. e optimization of treatment procedures and development of new suitable surface designs is therefore critically needed. In this study, several key steps for fluorescent nanodiamond treatment have been optimized, leading to both a substantial increase in fluorescence intensity and to significantly lower surface damage caused by graphitization. Further, a new high-throughput irradiation technique was developed. e influence of surface chemistry on the fluorescence parameters was studied using partial fluorination of the functional groups on the nanodiamond surface. A novel method which significantly affects the interaction of nanodiamonds with biological systems by increasing of the homogeneity and circularity was developed. e potential of nanodiamonds for future medical and biological research was demonstrated on particles with complex surface architectures that enabled targeting and therapy of tumor cells. Moreover, a strong and highly selective affinity of fibroblast growth factors to diamond...
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