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Ecotoxicological Evaluation of Polymers and Biologically Active Substances in Aquatic Environments
Kašpar, Otakar ; Beklová, Miroslava (referee) ; Chýlková, Jaromíra (referee) ; Kráčmar, Stanislav (referee) ; Vávrová, Milada (advisor)
To determine the ecotoxicity of analgetics, first the individual ecotoxicity values of individual analgetics are determined and then a mixture of two analgetics is tested. To determine the toxicity, both standard and alternative toxicity tests are used (daphnia magna, sinapsis alba, scenedesmus subspicatum, vibrio fischeri, thamnotoxkit FTM a daphnotoxkit FTM magna). The analgetics being whish tested are the commonly used medicines ibuprofen, ASA, diclofenac and paracetamol, which are the most frequently used medicines in the Czech Republic and whole Europe. To determine the ecotoxicity of the polymers, I‘m using an indirect method of examination, in which I determine the antagonistic or synergistic effects of the mixture of monomers from which the polymer is prepared and into which it slowly decomposes in nature. For the determination both standard and alternative toxicity tests are used. The polymers the toxicity of which is being determined are the habitually used polymer PET and the formaldehyde resine known as bakelite in Eastern Europe.
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Utilization of organism Daphnia magna in ecotoxicity tests
Winklerová, Lucie ; Vávrová, Milada (referee) ; Zlámalová Gargošová, Helena (advisor)
This thesis deals with ecotoxicity tests of selected substances used in agriculture and horticulture. It is focused on the determination of acute and chronic toxicity of selected herbicides. These herbicides are sold commercially, specifically Finalsan (active substance is nonanoic acid), the product of Neudorff GmbH KG company, and Dominator (active substance is glyphosate, isopropylamine salt) by Dow AgroSciences Ltd. Next tested substances are potassium nitrate and sodium nitrate - common agricultural fertilizers. Potassium dichromate was also tested. Potassium dichromate is very toxic for aquatic environment and it is used as the standard in acute tests. Tests were carried out in terms of effects on aquatic systems, due to very good solubility in water of selected substances. The tests were performed on the organism Daphnia magna.
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