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The effect of microfluidic sperm separation on the success of IVF therapy
NOVÁKOVÁ, Pavla
More and more couples are coming to assisted reproduction centres to solve conception problems. Despite initial efforts to improve lifestyle and reduce daily stress, problems in conceiving and delivering a healthy baby can be caused by one or a combination of multiple factors, and in such cases infertile couples opt for assisted reproductive treatment. In earlier times, the focus in the field of reproductive medicine was mainly on female fertility. In recent years, assisted reproductive medicine has largely focused on the field of andrology. In this regard, the development of enhanced spermiogram methods and sperm processing techniques has been developed. The current trend in reproductive embryology and andrology methods is to mimic the in vivo environment as much as possible. The aim of this bachelor's thesis was to determine whether the method of microfluidic sperm separation has an effect on sperm quality and whether the use of sperm obtained in this way influences the success of IVF treatment. In order to achieve the objectives of this study, data from 129 couples who underwent treatment in our IVF centre by donated oocytes and at the same time sperm from fresh ejaculate were used. The sperm samples were divided into two groups, namely for processing by gradient centrifugation and separation by microfluidic chip. The sperm were then used for in vitro fertilization using intracytoplasmic sperm injection method. Cycles with donated oocytes were selected to minimize the influence of female factor. The results of this work indicate that sperm processing by microfluidic chip method has a positive impact on the success of IVF treatment.
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Suggestions for Reduction of Uneployment in the district of Blansko
Nováková, Pavla ; Sychrová,, Daniela (referee) ; Zinecker, Marek (advisor)
This thesis is focused on unemployment in the district of Blansko. The theoretical part deals with to description of theoretical knowledge related to labour market, unemployment and state employment policy. The analytic part focuses on the statistical and graphical description of data concerning the current state of unemployment. The last part is devoted to proposals of solutions that could lead to a reduction in unemployment in this district.
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Aquaria Production Bukovany
Nováková, Pavla ; Štikar, Jaroslav (referee) ; Nový, Alois (advisor) ; Donaťáková, Dagmar (advisor)
The bachelor’s thesis is based on an architectural study worked up in the fourth semester of the bachelor’s study during the subject Ateliér architektonické tvorby III – AG033. The aim of the subject was the design of an industrial object designed for the production of aquaria on an assigned parcel in the village Bukovany near Kyjov. Not only was there a need for the design of production areas, but it was also necessary to design areas for the production of related furniture, an administrative area and a showroom for the presentation of products. The objective of the thesis was the creation of a construction study, the documentation for the execution of the project and an architectonic detail for the designed building. The assigned parcel is located on the edge of the village of Bukovany, in a relatively calm part of the village surrounded by a football field, cemetery and a former agricultural area. The designed object is formed of 6 separated areas – an administrative area, an exhibition and entry area, a production area, a woodworking area, a storage area and a technical area. The building is formed of a ground floor and one underground floor. Structurally the building is designed on a 6-meter module and the mixed structural system is used. For lighting the areas continuous saddle skylights are used, which switch to vertical elements on the edges of the building. The surroundings of the building are landscaped, including a resting area with a small lake on the southern part of the parcel.
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Sports and Relaxation Centre Za Lužánkami, Brno
Nováková, Pavla ; Vostrejž, Dušan (referee) ; Odvárka, Antonín (advisor)
The diploma thesis is based on a design of a sports recreational centre in Brno za Lužánkami. The area has a very rich sports history (former football stadium, ice arena, swimming pool,…), with great importance for the city of Brno and its residents. Due to the decay and bad technical condition of the structures, sports activity Za Lužánkami was suppressed at the end of the last century, and its return to the location is very current. The goal of the thesis was a design for the utilization of the area for various uses with a preference for leisure sports activities and offering options for all age groups during the entire year. In the first stage, an urban-architectural study was compiled, including a new functional use of the area for recreational sporting and relaxation, while being better connected with the surrounding localities. Following that, a complex architectural study of a multipurpose hall was designed in place of the former football stadium. The hall offers various possibilities for recreational sports, children‘s club training, talks and exhibitions hosting. Included are corresponding sanitary facilities, technical facilities, underground parking, commercial areas and a cafe. The structure is set in the ground and thanks to the variable roof inclination the rooftop park is directly accessible from the ground. The roof access is proposed from four places and offers further relaxation spots around the entire roof area.
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The foster care for temporary period of time from the point of view a foster parent
NOVÁKOVÁ, Pavla
This bachelor thesis deals with the foster care for a temporary period from the perspective of a professional foster caregiver. It focuses on motives leading to the performance of foster caring, secondly on foster parents´ perception of the foster care for temporary period and coping with the departure of the child to the following care. The work is divided into two parts. The first theoretical part deals with the general terms of substitute family care, especially the foster care for temporary period and personal qualities of a foster parent. In the practical part, eleven interviews were done with the temporary-period foster caregivers, who have got the experience of at least one end of placement of a child and fostering for at minimum two years. For finding out results, in-depth narrative interviews were done, these were subjected to interpretative phenomenological analysis (IPA).
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Use of Josef Lada´s pictures of months for developing the skill of a verbal describing with preschool children.
NOVÁKOVÁ, Pavla
This thesis deals with the findings of childrens´progress in picture description of Josef Lada´s paintings of months of the year. It shows the possibility to develop skills of describing a picture independently in pre-school children. In the theoretic part, there is defined monologic verbal language development of children, within pre-school age, possibilities of progress in using the speech coherenty and independently, methodical development of picture description, diagnostics of monologic spoken language and characteristics of Josef Lada´s images of months. In the practical part, verbal skills are tested with the help of 12 pictures of months by Josef Lada. The task is to describe these images. Testing is done on 2 groups of children and the levels of their description skills are looked into. These skills are continuously developed in one selected group. The results of the survey are presented at the end of the thesis. There are possible changes in children´s picture description skills after the evolving program and also differences in the picture description task between two groups of children are discovered by observation.
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Sports and Relaxation Centre Za Lužánkami, Brno
Nováková, Pavla ; Vostrejž, Dušan (referee) ; Odvárka, Antonín (advisor)
The diploma thesis is based on a design of a sports recreational centre in Brno za Lužánkami. The area has a very rich sports history (former football stadium, ice arena, swimming pool,…), with great importance for the city of Brno and its residents. Due to the decay and bad technical condition of the structures, sports activity Za Lužánkami was suppressed at the end of the last century, and its return to the location is very current. The goal of the thesis was a design for the utilization of the area for various uses with a preference for leisure sports activities and offering options for all age groups during the entire year. In the first stage, an urban-architectural study was compiled, including a new functional use of the area for recreational sporting and relaxation, while being better connected with the surrounding localities. Following that, a complex architectural study of a multipurpose hall was designed in place of the former football stadium. The hall offers various possibilities for recreational sports, children‘s club training, talks and exhibitions hosting. Included are corresponding sanitary facilities, technical facilities, underground parking, commercial areas and a cafe. The structure is set in the ground and thanks to the variable roof inclination the rooftop park is directly accessible from the ground. The roof access is proposed from four places and offers further relaxation spots around the entire roof area.
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Using linear semiconductor detector for testing the properties of linear accelerator
Menclová, Lucie ; Nováková, Pavla (advisor) ; Koniarová, Irena (referee)
A basic requirement for all therapeutic applications of ionizing radiation is the high accuracy of delivery of the prescribed dose to the target volume of tissue healing. Each radiotherapy department must have in the quality assurance program developed methodology for testing the operational stability, which are reviewed and approved by The State Office for Nuclear Safety (SÚJB). A part of testing the operational stability of linear accelerators is also a regular assessment and measurement of parameters of radiation field, which is done by measuring the dose profiles. The thesis presents the results of measurement and evaluation of photon beam dose profiles of a linear accelerator, measured using the line-semiconductor detector (LDA-99SC company IBA) in the automatic water phantom under the reference conditions and their comparison with results obtained from measurement with the ionization chamber under the same terms of reference. The advantage of using a linear detector is a semiconductor that consists of 99 individual detectors in one line at a distance of 5 mm from each other and is able to measure the radiation dose profile field in a much shorter time than using an ionization chamber, where only one detector output can measure dose point after point. Usage of any other independent system for...
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