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Treatment of a Patient after microdiscectomy of L4/L5
Evangelou, Angela ; Vomáčková, Helena (advisor) ; Ptáčková, Markéta (referee)
Title of the thesis: Treatment of a Patient after microdiscectomy of L4/L5 Thesis aim: This thesis involves a case study approach regarding to a patient after microdiscectomy of L4/L5. The thesis is divided into theoretical part which describes the anatomy and physiology of vertebral column and intervertebral disc. It also contains surgical and rehabilitation approach. The second is a health chart which contains the procedures I have done with my patient, all the examinations, conclusions, therapies and results. Methods: The practical part is based on a female patient of age 32, after microdiscectomy of L4/L5. The study consists of the initial kinesiologic examination, 4 practical therapy sessions and 3 theoritical sessions. It consist also the final kinesiologic examinations. All methods used were non-invasive. Result: After the therapy sessions my patient had a progress. Range of motion was increased, muscle tone and length was improved. The therapies have shown to be very effective concerning my patient's diagnosis.
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In vitro and in vivo studies of the neuroprotective peptide humanin using 125I-radiolabeled humanin derivatives
Evangelou, A. ; Zikos, C. ; Benaki, D. ; Pelecanou, M. ; Bouziotis, P. ; Papadopoulos, M. ; Borovičková, Lenka ; Veselá, Iva ; Elbert, Tomáš ; Kunešová, G. ; Pirmettis, I. ; Paravatou-Petsotas, M. ; Slaninová, Jiřina ; Livaniou, E.
Four new HN-derivatives were synthesized: Y-PAGASRLLLTGEIDLP (Y-des-Leu-RG-PAGA, 1), Y-PAGASRLLLLTGEIDLP (Y-RG-PAGA, 2), Y-SALLRSIPAPAGASRLLLTGEIDLP (Y-des-Leu-Colivelin, 3), Y-SALLRSIPAPAGASRLLLLTGEIDLP (Y-Colivelin, 4), their neuroprotective action was evaluated in the T-maze test and the most active ones were monoradioiodinated with 125I and the labelled peptides used for binding and biodistribution studies.
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