guest :: login Digital Repository
		Search		Submit		Help		About

Home > Research > Institutes ASCR > Institute of Microbiology > Search Results

Institute of Microbiology

Search:



Search Tips :: Simple Search

Search collections:

Sort by:	Display results:	Output format:

	Vyhledávání jaderného transportinu faktoru ISW1 remodelujícího chromatin u Saccharomyces cerevisiae Strádalová, Vendula ; Hašek, Jiří ; Janatová, Ivana Several intragenously-tagged versions of the ISW1 gene were constructed to follow Isw1p localization either in living (GFP-fusions) or in fixed cells (c-Myc-fusions). The whole set of available importin mutants was transformed with vectors carrying an intragenously-tagged ISW1 gene. In the strains where the importins Kap120p, Nmd5p, Sxm1p, Kap114p, Los1p, Msn5p, Kap123p and Pdr6 were deleted, the Isw1p-GFP fusion regulated by the ISW1 promoter was localized always in the nucleus. This suggests that none from these importins is required for nuclear localization of Isw1p. The localization of the Isw1p-GFP in the mtr10-1 strain differed from that observed in all the other analyzed importin mutants. Our results indicate that Mtr10p could be a good candidate for Isw1p importin. Detailed record
	Analysis of the catechol degradation operon from Rhodococcus erythropolis Veselý, Martin ; Pátek, Miroslav Three genes of phenol-degrader Rhodococcus erythropolis involved in degradation of catechol and one gene coding for their activator were isolated and characterized.The obtained knowledge will contribute to construction of strains with more efficient phenol degradation. Detailed record
	Bioavailability of PAH and its effects on biodegradation during composting Cajthaml, Tomáš ; Hubálek, Tomáš ; Šašek, Václav The publication deals with application of composting process on remediation of soils contaminated with PAHs. Bioavailability of PAHs was tested with sequential SFE and the data were compared with the results of remediation. SFE is suitable to predict results of bioremediation. Detailed record
	Role segmentované filamentozní bakterie (SFB) u experimentální kolitidy vyvolané u SCID myší rekonstituovaným přenosem CD4+CD45RB/hi T lymfocyty Štěpánková, Renata ; Tlaskalová, Helena ; Powrie, F. ; Kozáková, Hana ; Hudcovic, Tomáš Colitis was present only in conventional SCID mice and mice colonized with defined cocktail microflora plus segmented filamentous bacteria (SFB). Altered tight junctions (TJs) structure was detect histochemically in colitic mice using antibodies against ZO-1 proteins. Structural changes of TJs was important feature of intestinal inflammation Detailed record
	Antracyklinová antibiotika na bázi protilátkou směrovaného HPMA Říhová, Blanka ; Strohalm, Jiří ; Jelínková-Ibrahimová, Markéta ; Kovář, Marek ; Šubr, Vladimír ; Etrych, Tomáš ; Mrkvan, Tomáš ; Šťastný, Marek ; Plocová, Daniela ; Šírová, Milada ; Hovorka, Ondřej ; Kubáčková, K. ; Ulbrich, Karel Conjugates based on N-(2-hydroxypropyl)methacrylamide represent a new generation of polymeric anticancer drugs with improved therapeutic potential and considerably decreased nonspecific side effects. Antibody -targeted derivatives show specific active targeting and nonspecific passive accumulation in solid tumors. Detailed record
	Modulace metabolických toků biosyntetickými drahami aminokyselin s větveným řetězcem u Corynebacterium glutamicum Pátek, Miroslav ; Elišáková, Veronika ; Holátko, Jiří Metabolic fluxes in pathways of biosynthesis of branched-chain amino acids can be modulated by different changes in expression of genes of the desired pathway as well as those of competing pathways. Site-directed mutagenesis of promoters of the respective genes is a suitable tool to obtain desired changes in gene expression. Detailed record
	Konstrukce kmenů Corynebacterium glutamicum s nadprodukcí valinu Elišáková, Veronika ; Holátko, Jiří ; Pátek, Miroslav Promoters of genes involved in biosynthesis of branched-chain amino acids in Corynebacterium glutamicum were mutagenized. The promoters with increased or decreased activities were used for construction of novel valine-overproducing strains Detailed record
	Plasmidové vektory pro genové manipulace u Rhodococcus erythropolis Veselý, Martin ; Knoppová, Monika ; Pátek, Miroslav Vectors for rhodococci, based on plasmids from corynebacteria, were constructed. They are used for gene cloning and analysis of gene expression in phenol-degrading rhodococci. Detailed record
	Role segmentované filamentozní bakterie (SFB) u experimentální kolitidy vyvolané u SCID myší rekonstituovaným přenosem CD4+CD45RB/hi T lymfocyty Štěpánková, Renata ; Tlaskalová, Helena ; Powrie, F. ; Kozáková, Hana ; Hudcovic, Tomáš ; Kofroňová, Olga Colitis was present only in conventional SCID mice and mice colonized with defined cocktail microflora plus segmented filamentous bacteria (SFB). Altered tight junctions (TJs) structure was detect histochemically in colitic mice using antibodies against ZO-1 proteins. Structural changes of TJs was important feature of intestinal inflammation Detailed record
	Exprese genů pro signalizaci apoptozy u buněk vystavených účinku HPMA konjugátů doxorubicinu Kovář, Lubomír ; Kovář, Marek ; Šťastný, Marek ; Strohalm, Jiří ; Etrych, Tomáš ; Ulbrich, Karel ; Říhová, Blanka We compared influence of hydrolytically and enzymatically cleavable conjugates based on N-(2-hydroxypropyl)methacrylamide on proliferatin activity and expression of mRNA of genes involved in apoptotic signalling pathway. We found elevated expression of Fas and bax mRNA in cells incubated with hydrolytically cleavable conjugates. Detailed record

Interested in being notified about new results for this query?
Subscribe to the RSS feed.

Digital Repository :: :: :: ::
Powered by v1.1.2
Maintained by

This site is also available in the following languages:
Česky English