Original title: Purinové deriváty v léčbě vlasatobuněčné leukémie
Translated title: Purine analogs in treatment of Hairy cell leukemia
Authors: ŠVECOVÁ, Ivana
Document type: Bachelor's theses
Year: 2011
Language: cze
Abstract: This thesis is about significant role of purine nukleoside analogs in the treatment of indolent lymphoproliferative disorder, named Hairy cell leukemia. Preliminary there is description of this uncommon disease and possibilities of it´s detection is included. Studies with two purine analogues deoxycoformycin and 2-chlorodeoxyadenosine and their mechanism of action are mentioned. Then comparisons with older variants of treatment and introducing some novel cytotoxic agents like a therapeutic strategies for patients with relapsed disease are discussed.
Keywords: cladribine; hairy cell leukemia; pentostatin; rituximab; kladribin; pentostatin; rituximab; vlasatobuněčná leukémie
Citation: ŠVECOVÁ, Ivana. Purinové deriváty v léčbě vlasatobuněčné leukémie. České Budějovice, 2011. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/22653

Permalink: http://www.nusl.cz/ntk/nusl-79989


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses