Original title: Electrochemistry of Sudan I and its derivates in aqueous media
Authors: Ondráčková, Anna ; Stiborová, M. ; Havran, L. ; Schwarzová-Pecková, Karolina ; Fojta, Miroslav
Document type: Papers
Conference/Event: 16th Annual International Students Conference on Modern Analytical Chemistry, Praha (CZ), 20200917
Year: 2020
Language: eng
Abstract: Sudan I is an aromatic azo-compound that has been proven to be a carcinogen. During its metabolization by cytochrome P450 in liver a few main derivates can be identified. This work sets out to assess the mechanism of electrochemical reduction and oxidation of Sudan I, its hydroxylation derivatives featuring metabolites in the Sudan I detoxification pathway and to introduce their selective voltammetric analysis on boron-doped diamond electrode. We show successful differentiation among these compounds, thanks to the differences in the electrochemical oxidation of their phenolic groups.
Keywords: boron doped diamond electrode; cytochrome P450; electrochemical analysis; Sudan I
Host item entry: PROCEEDINGS OF THE 16TH INTERNATIONAL STUDENTS CONFERENCE MODERN ANALYTICAL CHEMISTRY, ISBN 978-80-7444-079-3

Institution: Institute of Biophysics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0362295

Permalink: http://www.nusl.cz/ntk/nusl-669379


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