Original title: Portable emissions toxicity system: compact air-liquid interface system for exposure of cell cultures to diluted emissions and polluted air
Authors: Vojtíšek, M. ; Dittrich, L. ; Pechout, M. ; Červená, Tereza ; Vimrová, Anežka ; Sikorová, Jitka ; Závodná, Táňa ; Ondráček, Jakub ; Topinka, Jan ; Rössner ml., Pavel
Document type: Papers
Conference/Event: SBORNÍK XXIII. výroční konference České aerosolové společnosti OVZDUŠÍ V ČASe, Milovy (CZ), 20241111
Year: 2024
Language: eng
Abstract: Exposure of living cell cultures at air-liquid interface (ALI), mimicking i.e. human lung surface, is believed to be one of the most realistic means to model toxicity of complex mixtures of pollutants on human health. The complexity of the close cooperation of “emissions source” and toxicology groups and of the instrumentation are among the limiting factors of ALI.\nHere, the concepts of ALI exposure and real-world emissions monitoring using portable emissions monitoring systems (PEMS) are combined into a portable emissions toxicity systems (PETS), along with a mobile toxicological laboratory base, for field deployment, including operation in moving vehicles.
Keywords: air-liquid interface; emissions; exposure; portable emissions monitoring system; real-world emissions; toxicity
Project no.: GA22-10279S (CEP), LM2023030 (CEP)
Funding provider: GA ČR, GA MŠk
Host item entry: PROCEEDINGS OF 23rd Annual Conference of the Czech Aerosol Society OVZDUŠÍ V ČASe, ISBN 978-80-908653-2-7

Institution: Institute of Experimental Medicine AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0361759

Permalink: http://www.nusl.cz/ntk/nusl-669202


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Research > Institutes ASCR > Institute of Experimental Medicine
Conference materials > Papers