Original title: Hormonální kontrola obraných reakcí vůči přírodním toxinům
Authors: ČERNÝ, Jan
Document type: Doctoral theses
Year: 2024
Language: eng
Abstract: This PhD thesis explores the hormonal and physiological responses of insect models to natural hymenopteran toxins, particularly focusing on the honeybee Apis mellifera and the minute wasp Habrobracon hebetor venoms. It also addresses the role of adipokinetic hormone in resisting these venoms. Further, the study analyses potential pharmacological applications of melittin, a key bee venom component. Additionally, it shows that the honeybee stinger, far from being a passive structure, actively contributes to venom's destructive effects and it is a living organ. The research also presents Drosophila melanogaster as a useful model for studying venom toxin activities, contributing to potential drug discoveries and advancements in toxicology.
Keywords: adipokinetic hormone; anti-stress defense reaction; Apis mellifera venom; Drosophila melanogaster; Habrobracon hebetor venom; hymenopteran stinger microstructure; immune-related genes; melittin; muscle (ultra)structure; oxidative stress
Citation: ČERNÝ, Jan. Hormonální kontrola obraných reakcí vůči přírodním toxinům. České Budějovice, 2024. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/62353

Permalink: http://www.nusl.cz/ntk/nusl-662686


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Doctoral theses