Original title:
Stanovení perzistentních organohalogenových polutantů metodou GC/MS/MS
Translated title:
Determination of persistent organohalogen pollutants using GC/MS/MS methods
Authors:
Grabic, Roman ; Pacáková, Věra (advisor) ; Ševčík, Jiří (referee) ; Matisová, Eva (referee) Document type: Doctoral theses
Year:
2006
Language:
cze Abstract:
Conclusions o MSiMS methods for analysis of PCDD/Fs, PCBs, OCPs, and PBDES were develoPed o GC separations were optimized for MS/MS detection methods o GC/MS/MS optimized methods were validated. o Limits of quantification at level 0.1 - I pg/pl were achieved. o Linear response over four orders of magnitude was achieved except for some OCPs. o The selectivity of methods is better or comparable with a reference HRMS method' o Cost of GC/MS/MS analysis is significantly lower comPared to GC/HRMS o Developed methods were successfully applied for o Human blood, milk and adipose tissue analysis o Studies of de novo synthesis and destruďion of halogenated POP o In vitro study of PCB accumulation in human cells o List of application is enclosed Page 12
Institution: Charles University Faculties (theses)
(web)
Document availability information: Available in the Charles University Digital Repository. Original record: http://hdl.handle.net/20.500.11956/95741