Original title: Chronoterapie jako nový trend v léčbě hypertenze
Translated title: Chronotherapy as a new trend in the treatment of hypertension
Authors: Pafková, Patrícia ; Sumová, Alena (advisor) ; Alánová, Petra (referee)
Document type: Bachelor's theses
Year: 2024
Language: slo
Abstract: [eng] [cze]
Hypertension is still the leading cause of death and cardiovascular morbidity worldwide, but its long-term control remains unsatisfactory. Blood pressure is subject to certain variability during 24 hours, when its values are 10-20% lower at night than during the day. Due to the new knowledge that the circadian rhythm exists in almost all organ systems, interest in chronotherapy as a new trend in treatment is growing. This bachelor's thesis points out the importance of respecting circadian rhythms and includes current knowledge about chronotherapy of hypertension, together with an analysis of its benefits in the treatment of high blood pressure. Keywords: hypertension, circadian rhytm, antihypertensives, chronotherapy, blood pressure Hypertenzia stále predstavuje celosvetovo hlavnú príčinu smrti a kardiovaskulárnej morbidity, no jej kontrola ostáva dlhodobo neuspokojivá. Krvný tlak podlieha počas 24 hodín určitej variabilite, kedy sú jeho hodnoty v noci o 10-20 % nižšie ako cez deň. Narušenie prirodzeného cirkadiánneho rytmu TK je spájané so zhoršenou kardiovaskulárnou prognózou. Vzhľadom na nové poznatky, že cirkadiánny rytmus existuje takmer vo všetkých orgánových systémoch, rastie záujem o chronoterapiu ako nový trend v liečbe. Táto bakalárska práca poukazuje na dôležitosť rešpektovania cirkadiánnych rytmov a zahŕňa aktuálne poznatky o chronoterapii hypertenzie, spolu s analýzou jej benefitov pri liečbe vysokého krvného tlaku. Kľúčové slová: hypertenzia, cirkadiánny rytmus, antihypertenzíva, chronoterapia, krvný tlak
Keywords: antihypertensives; blood pressure; chronotherapy; circadian clock; hypertension; antihypertenzíva; chronoterapie; cirkadiánní hodiny; hypertenze; krevní tlak

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/190107

Permalink: http://www.nusl.cz/ntk/nusl-620854


The record appears in these collections:
Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Bachelor's theses