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Original title:
Improvement of an unbaffled stirred tank mixing characteristics using variable speed impeller
Authors: Gebouský, Ondřej ; Haidl, Jan ; Bodnár, J. ; Pivokonský, Martin
Document type: Papers
Conference/Event: Topical Problems of Fluid Mechanics 2024, Prague (CZ), 20240221
Year: 2024
Language: eng
Abstract: Unbaffled mixing tanks with magnetically driven impellers are increasingly used in biotechnological and pharmaceutical industries, combining the benefits of a closed, sterile environment with easy equipment cleanability. On the other hand, missing internals, such as baffles or cooling coils, have an adverse effect on the equipment mixing characteristics, namely the batch\nhomogenization time. In our previous research, we uncovered that the eccentricity and inclination of the impeller – both employed routinely to enhance the mixing characteristics of unbaffled vessels – are not fully effective in the suppression of central vortex formation resulting in the increase in the homogenization time. In this work, we propose a simple solution to counteract the central vortex formation – a periodical variation of impeller rotational speed. This approach destabilizes the central vortex, significantly reducing homogenization time while maintaining the benefits of the original unbaffled setup. This innovation can seamlessly integrate into existing industrial setups, promising efficiency gains for biotech and pharmaceutical production.
Keywords: mixing time improvement; unbaffled mixing tanks; variable rotational speed; vortex destabilization
Project no.: StrategieAV21/20, AP2201
Funding provider: AV ČR, AV ČR
Host item entry: Topical Problems of Fluid Mechanics, ISBN 978-80-87012-88-8, ISSN 2336-5781
Note: Související webová stránka: http://www2.it.cas.cz/fm/im/im/proceeding/2024/8
Institution: Institute of Hydrodynamics AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0353398
Permalink: http://www.nusl.cz/ntk/nusl-614324
The record appears in these collections:
Research > Institutes ASCR > Institute of Hydrodynamics
Conference materials > Papers
Authors: Gebouský, Ondřej ; Haidl, Jan ; Bodnár, J. ; Pivokonský, Martin
Document type: Papers
Conference/Event: Topical Problems of Fluid Mechanics 2024, Prague (CZ), 20240221
Year: 2024
Language: eng
Abstract: Unbaffled mixing tanks with magnetically driven impellers are increasingly used in biotechnological and pharmaceutical industries, combining the benefits of a closed, sterile environment with easy equipment cleanability. On the other hand, missing internals, such as baffles or cooling coils, have an adverse effect on the equipment mixing characteristics, namely the batch\nhomogenization time. In our previous research, we uncovered that the eccentricity and inclination of the impeller – both employed routinely to enhance the mixing characteristics of unbaffled vessels – are not fully effective in the suppression of central vortex formation resulting in the increase in the homogenization time. In this work, we propose a simple solution to counteract the central vortex formation – a periodical variation of impeller rotational speed. This approach destabilizes the central vortex, significantly reducing homogenization time while maintaining the benefits of the original unbaffled setup. This innovation can seamlessly integrate into existing industrial setups, promising efficiency gains for biotech and pharmaceutical production.
Keywords: mixing time improvement; unbaffled mixing tanks; variable rotational speed; vortex destabilization
Project no.: StrategieAV21/20, AP2201
Funding provider: AV ČR, AV ČR
Host item entry: Topical Problems of Fluid Mechanics, ISBN 978-80-87012-88-8, ISSN 2336-5781
Note: Související webová stránka: http://www2.it.cas.cz/fm/im/im/proceeding/2024/8
Institution: Institute of Hydrodynamics AS ČR (web)
Document availability information: Fulltext is available in the digital repository of the Academy of Sciences.
Original record: https://hdl.handle.net/11104/0353398
Permalink: http://www.nusl.cz/ntk/nusl-614324
The record appears in these collections:
Research > Institutes ASCR > Institute of Hydrodynamics
Conference materials > Papers
Record created 2024-05-12, last modified 2024-08-17