Original title: Muscotoxins: novel cytotoxic undecapeptides with unique structural elements and mechanism of action, isolated from soil cyanobacterium \kur{Nostoc muscorum.}
Translated title: Muscotoxins: novel cytotoxic undecapeptides with unique structural elements and mechanism of action, isolated from soil cyanobacterium \kur{Nostoc muscorum}
Authors: TOMEK, Petr
Document type: Master’s theses
Year: 2010
Language: cze
Abstract: This project was focused on development of extraction and purification protocol for novel cytotoxic compound isolated from soil cyanobacterium Nostoc muscorum which would allow to determine its molecular structure via NMR (nuclear magnetic resonance) and MS (mass spectrometry) techniques. Purified cytotoxin was subjected to several biochemical and microscopical experiments in order to assess its toxicological parameters, determine the mechanism of action and evaluate potential application in biotechnology or pharmacy.
Keywords: cell; chromatography; cyanobacteria; cytotoxicity; cytotoxin; muscotoxin; Nostoc; secondary metabolites; spectrometry
Citation: TOMEK, Petr. Muscotoxins: novel cytotoxic undecapeptides with unique structural elements and mechanism of action, isolated from soil cyanobacterium \kur{Nostoc muscorum.}. České Budějovice, 2010. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/9734

Permalink: http://www.nusl.cz/ntk/nusl-53236


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Master’s theses