Original title: Diffusion Behavior of Analyte Molecules in a Nanoporous Matrix Created from Polystyrene Nanoparticles
Authors: Košelová, Zuzana
Document type: Papers
Language: eng
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: This study investigates the diffusion behavior ofanalyte molecules in a nanoporous matrix of polystyrene particles.Two approaches, steady-state current and potential stepchronoamperometry were employed to calculate diffusioncoefficients and compare the effect of nanoporous matrices withdifferent diameter of pores and different method ofimmobilization of enzyme. Pores were created with close packingof polystyrene nanoparticles. The covalent and cross-linkingimmobilization were used to immobilize the enzyme.Chronoamperometric measurement was applied to detect analyte.The study found that the presence of nanoporous matricesimmobilized on p-lysine affects diffusion. The potential stepchronoamperometry method showed the improvement ofdiffusion. This study provides insight into the diffusion behaviorof analyte molecules in nanoporous matrices, which can be usefulin optimizing the design of amperometric biosensors.
Keywords: Diffuse coefficient; nanoporous matrix; polystyrene nanoparticles; potentialstep chronoamperometry; steady-statecurrent
Host item entry: Proceedings II of the 29st Conference STUDENT EEICT 2023: Selected papers, ISBN 978-80-214-6154-3, ISSN 2788-1334

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/210700

Permalink: http://www.nusl.cz/ntk/nusl-531806


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