Original title: Orthohantaviruses in the reservoir and atypical hosts in the Czech Republic: spillover infection and indication of virus-specific tissue tropism
Authors: KAMIŠ, Jan
Document type: Rigorous theses
Year: 2022
Language: eng
Abstract: Aim of this study was to reveal the presence of hantaviruses in natural reservoir rodent hosts in selected urban areas in the Czech Republic. Hantavirus rodent hosts were trapped, sampled and tested for hantavirus RNA in different tissues. Universal and specific primers for amplification of the large and medium fragments of hantavirus genomic RNA were used. Phylogenetic relationships were based on the obtained nucleotide sequences. Four different hantaviruses were detected, including two species pathogenic (or potentially pathogenic) for humans, further suggesting a threat for public health. Moreover, inter-family spillover infections and hantavirus species-associated tissue tropism were recorded in rodent hosts.
Keywords: Asikkala virus; hantavirus; host specificity; Kurkino virus; phylogeny; Seewis virus; spillover infection; tissue specificity; Tula virus
Citation: KAMIŠ, Jan. Orthohantaviruses in the reservoir and atypical hosts in the Czech Republic: spillover infection and indication of virus-specific tissue tropism. České Budějovice, 2022. rigorózní práce (RNDr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/69901

Permalink: http://www.nusl.cz/ntk/nusl-519811


The record appears in these collections:
Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Rigorous theses