Home > Academic theses (ETDs) > Master’s theses > Identification of physical and chemical factors regulating gene expression and infectivity of the Lyme disease spirochetes
Original title:
Identification of physical and chemical factors regulating gene expression and infectivity of the Lyme disease spirochetes
Authors:
PAVLASOVÁ, Veronika Document type: Master’s theses
Year:
2022
Language:
cze Abstract:
Borrelia afzelii is one of the main Lyme disease causative agents. It is known that differential gene expression during the Borrelia life cycle can relate to infectivity for mammals, including humans. However, just a little is known about what affects these changes in expression. Here, we investigate the effect of temperature and common blood nutrients on Borrelia afzelii differential gene expression and transmission efficiency while stimulating the ticks with chosen substances.
Keywords:
amino acids; bbk32; Borrelia; gene expression; Ixodes; Lyme disease; ospA; ospC; qPCR; qRT-PCR; sugars; ticks Citation: PAVLASOVÁ, Veronika. Identification of physical and chemical factors regulating gene expression and infectivity of the Lyme disease spirochetes. České Budějovice, 2022. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
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Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/64550