Original title:
The role of Q tRNA modification in codon biased translation in \kur{Leishmania mexicana}
Authors:
ŠVÁBOVÁ, Monika Document type: Master’s theses
Year:
2022
Language:
eng Abstract:
The aim of the thesis was to standardize polysome profiling and ribosome profiling protocols for the parasitic protist Leishmania mexicana in order to identify the effect of Q-tRNAs in translation. In addition, we analyzed the role of queuosine (Q) t-RNA modification in the cell cycle of L. mexicana. The proteomics analysis was carried out in order to elucidate the role of Q-tRNAs in protein folding.
Keywords:
Leishmania mexicana; modification; polysome profiling; queuosine; ribosome profiling; translation; tRNA Citation: ŠVÁBOVÁ, Monika. The role of Q tRNA modification in codon biased translation in \kur{Leishmania mexicana}. České Budějovice, 2022. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/63725