Original title: Úloha osy PD-1/PD-L1 při infekci \kur{Borrelia burgdorferi} u myší
Authors: PALOUNKOVÁ, Anna
Document type: Bachelor's theses
Year: 2022
Language: cze
Abstract: Borrelia burgdorferi, the causative agent of Lyme disease, induces upregulation of inhibitory immune checkpoint PD-L1 in mice. We studied if the blockade of PD-1/PD-L1 axis by neutralizing antibodies influences the proliferation of T lymphocytes and cytokine milieu in imunological synapsis between murine dendritic cells and T cells in vitro.
Keywords: anti-PD-L1; antibody; Borrelia; Borrelia burgdorferi; dendritic cell; immune checkpoint; infection; lyme disease; mice; PD-1; PD-L1; pDC; proliferation; T lymfocytes; Borelie; dendritická buňka; imunitní kontrolní body; infekce; lymeská borelióza; myši; proliferace; protilátka; T lymfocyty
Citation: PALOUNKOVÁ, Anna. Úloha osy PD-1/PD-L1 při infekci \kur{Borrelia burgdorferi} u myší. České Budějovice, 2022. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/62657

Permalink: http://www.nusl.cz/ntk/nusl-517328


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses