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> Úloha osy PD-1/PD-L1 při infekci \kur{Borrelia burgdorferi} u myší
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Original title:
Úloha osy PD-1/PD-L1 při infekci \kur{Borrelia burgdorferi} u myší
Authors:
PALOUNKOVÁ, Anna
Document type:
Bachelor's theses
Year:
2022
Language:
cze
Abstract:
Borrelia burgdorferi, the causative agent of Lyme disease, induces upregulation of inhibitory immune checkpoint PD-L1 in mice. We studied if the blockade of PD-1/PD-L1 axis by neutralizing antibodies influences the proliferation of T lymphocytes and cytokine milieu in imunological synapsis between murine dendritic cells and T cells in vitro.
Keywords:
anti-PD-L1
;
antibody
;
Borrelia
;
Borrelia burgdorferi
;
dendritic cell
;
immune checkpoint
;
infection
;
lyme disease
;
mice
;
PD-1
;
PD-L1
;
pDC
;
proliferation
;
T lymfocytes
;
Borelie
;
dendritická buňka
;
imunitní kontrolní body
;
infekce
;
lymeská borelióza
;
myši
;
proliferace
;
protilátka
;
T lymfocyty
Citation:
PALOUNKOVÁ, Anna. Úloha osy PD-1/PD-L1 při infekci \kur{Borrelia burgdorferi} u myší. České Budějovice, 2022. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution:
University of South Bohemia in České Budějovice (
web
)
Document availability information:
Fulltext is available in the Digital Repository of University of South Bohemia.
Original record:
http://www.jcu.cz/vskp/62657
Permalink:
http://www.nusl.cz/ntk/nusl-517328
The record appears in these collections:
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>
University of South Bohemia in České Budějovice
Academic theses (ETDs)
>
Bachelor's theses
Record created 2023-01-15, last modified 2023-01-15
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