Original title: Elucidating the source of bloodstream \kur{Trypanosoma brucei} mitochondrial ATP
Authors: HUSOVÁ, Michaela
Document type: Master’s theses
Year: 2021
Language: eng
Abstract: For decades, it has been assumed that the reduced function and structure of the bloodstream form Trypanosoma brucei mitochondrion renders it a strictly ATP consuming organelle. Emerging evidence from refocused studies suggest that the bloodstream mitochondrion retains complex bioenergetic pathways that allow the parasite to adapt to various environments. This thesis is focused on the source of bloodstream mitochondrial ATP, with a special emphasis on the role of succinyl-CoA to produce ATP via mitochondrial substrate phosphorylation. We will also discuss alternative bioenergetic pathways present in this life stage of a human pathogen.
Keywords: bioenergetics; mitochondria; substrate phosphorylation; succinyl coenzyme A; Trypanosoma brucei
Citation: HUSOVÁ, Michaela. Elucidating the source of bloodstream \kur{Trypanosoma brucei} mitochondrial ATP. České Budějovice, 2021. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/60122

Permalink: http://www.nusl.cz/ntk/nusl-515970


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Master’s theses