Original title: Mass spectrometry in structural proteomics: study of viral protein complexes
Authors: RAVI, Anirudhan
Document type: Bachelor's theses
Year: 2021
Language: eng
Abstract: This thesis investigated the avian reovirus sigma NS protein and its interaction with RNA using mass spectrometric methods. The sigma NS structure is still not known; thus, hydrogen-deuterium exchange and cross-linking coupled to mass spectrometry were employed to understand protein conformation. This research provides insights into protein-RNA interactions and the obtained data will be used in future work to predict protein structure.
Keywords: 3D structure; Avian reovirus; cross-linking mass spectrometry.; hydrogen-deuterium exchange; matrix-assisted laser/desorption ionization; sigma NS protein
Citation: RAVI, Anirudhan. Mass spectrometry in structural proteomics: study of viral protein complexes. České Budějovice, 2021. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/59394

Permalink: http://www.nusl.cz/ntk/nusl-515520


The record appears in these collections:
Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses