Original title:
Recombinant production and characterization of protease domain from TBEV nonstructural protein NS3
Authors:
VEJVODOVÁ, Kateřina Document type: Master’s theses
Year:
2021
Language:
eng Abstract:
The aim of this thesis was to produce and characterize recombinant protease domain of TBEV nonstructural protein 3 (NS3). The NS3 protein of TBEV is essential in viral replication and plays an indispensable role in cleaving viral polyprotein into structural and nonstructural viral proteins, thus making it an attractive target for antiviral treatment. This thesis summarized the cloning of TBEV NS3 protease,production and purification of recombinant enzyme, biochemical and kinetic characterazion of the protease domain from TBEV NS3.
Keywords:
Flavivirus; nonstructural protein NS3; Tick-borne encephalitis virus Citation: VEJVODOVÁ, Kateřina. Recombinant production and characterization of protease domain from TBEV nonstructural protein NS3. České Budějovice, 2021. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/59200