Original title:
Detection of persistent forms of Borrelia burgdorferi sensu stricto in infected mice after antibiotic treatment
Authors:
RAMZY, Ida Document type: Bachelor's theses
Year:
2019
Language:
eng Abstract:
Antibiotic treatment of Lyme disease is a challenging procedure with unexpected outcomes that may arise sometime. According to standard protocols recommended by the Centers for Disease Control and Prevention, USA (CDC) for early Lyme disease, a short course of oral antibiotics cures the majority of cases. This thesis deals with the analysis of the efficiency of 2 majorly used antibiotics, doxycycline and amoxicillin, in elimination of Borrelia infection on laboratory mice model after 2 weeks of treatment. Our results confirmed the presence of persistent forms of spirochetes in mice tissues after antibiotic treatment using the spirochete cultivation method in liquid MKP medium.
Keywords:
amoxicillin; Borrelia burgdorferi; chronic Lyme disease; doxycycline; Lyme disease; parasitology; spirochetes Citation: RAMZY, Ida. Detection of persistent forms of Borrelia burgdorferi sensu stricto in infected mice after antibiotic treatment. České Budějovice, 2019. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/53043