Original title: Molecular Factors of Cell Antiviral Immunity
Authors: SELINGER, Martin
Document type: Doctoral theses
Year: 2019
Language: eng
Abstract: The proposed thesis focuses on the description of flavivirus-host interactions in case of tick-borne encephalitis virus (TBEV) and Zika virus (ZIKV). In more detail, the TBEV-induced host responses in human cells of neural origin and interferon-mediated protection were described together with the identification of a new phenomenon of TBEV-induced host transcriptional and translational shut-off. In addition, virus-derived molecules with hypothetical immunomodulatory characteristics, TuORF and ZIKV sfRNA, were analysed for their presence and possible function during the infection.
Keywords: flaviviruses; host response; interferon; neural cells; tick-borne encephalitis virus; Zika virus
Citation: SELINGER, Martin. Molecular Factors of Cell Antiviral Immunity. České Budějovice, 2019. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/35924

Permalink: http://www.nusl.cz/ntk/nusl-513418


The record appears in these collections:
Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Doctoral theses