Original title: Function of the Type IV pili proteins in the cyanobacterium Synechocystis sp. PCC 6803.
Authors: LINHARTOVÁ, Markéta
Document type: Doctoral theses
Year: 2021
Language: eng
Abstract: The thesis is focused on the function of the Type IV pili machinery in the cyanobacterium Synechocystis sp. PCC. 6803. In my work, I provided evidence that in phototrophs, some pilin proteins have acquired a novel function related to metal transport and assembly of photosynthetic complexes. The tight connection between the synthesis of the major pilin PilA1 and the biogenesis of photosynthetic complexes has been demonstrated in the pilD mutant lacking prepilins peptidase. I isolated and characterized pilD suppressor strains, which revealed the important role of the minor pilin PilA2 in the glycosylation of PilA1 and the restricted mobility of PilA1 prepilin in the membrane. My unpublished data indicate that the retraction mode of pili, driven by the PilT1 molecular motor, facilitates manganese uptake and the activity of this machine is critically important during the regulation from the exponential to the linear growth phase.
Keywords: major pilin; metal transport; photoautotrophy; photosystem II; PilD peptidase; prepilin toxicity; Synechocystis; type IV pili
Citation: LINHARTOVÁ, Markéta. Function of the Type IV pili proteins in the cyanobacterium Synechocystis sp. PCC 6803.. České Budějovice, 2021. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/16019

Permalink: http://www.nusl.cz/ntk/nusl-513365


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Doctoral theses