Original title: Příprava a vlastnosti biokompatiblních povrchů na bázi substituovaných polyakrylamidů
Translated title: Synthesis and properties of biocompatible polyacrylamide-coated surfaces
Authors: Kopilec, Ondrej ; Sedláček, Ondřej (advisor) ; Studenovský, Martin (referee)
Document type: Bachelor's theses
Year: 2022
Language: slo
Abstract: [eng] [cze]
This bachelor thesis focuses first on the synthesis of N-substituted acrylamide monomers for the following controlled radical polymerization into corresponding polyacrylamides. The prepared library of 16 polymers differs in side-chain group structure and degrees of polymerization. The next part is focused on the characterization of polyacrylamides, using NMR, MALDI - TOF and GPC techniques. Polymers were then grafted to golden wafers and the properties of these surfaces were studied. Thickness and grafting density of layers were measured, via spectroscopic ellipsometry, and water contact angle goniometry was measured to characterize the surface hydrophilicity. Bakalárska práca sa najprv venuje príprave N-substituovaných akrylamidov, ako použitých monomérov na následnú syntézu polyakrylamidov. Pomocou riadenej radikálovej polymerizácie metódou RAFT bolo pripravených šestnásť polyakrylamidov, s rôznymi bočnými skupinami a o rôznych stupňoch polymerizácie - 25, 50, 75 a 100. Ďalšia časť je venovaná charakterizácií polyakrylamidov pomocou NMR, MALDI-TOF a GPC techník. Polyméry boli následne pomocou techniky "grafting to" nasadené na zlaté doštičky a boli zisťované vlastnosti takto vzniknutého povrchu. Hrúbka tohto povrchu bola zmeraná pomocou elipsometrie, a ako charakter jeho hydrofilicity boli zmerané hodnoty zmáčanlivosti vodou.

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/175242

Permalink: http://www.nusl.cz/ntk/nusl-508093


The record appears in these collections:
Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Bachelor's theses