Original title: Malárie - globální výzva
Translated title: Malaria: the global challenge
Authors: Nicholson, Ashley ; Dáňová, Jana (advisor)
Document type: Master’s theses
Year: 2009
Language: eng
Abstract: More than half the world's population is at risk from malaria, with up to 500 million cases each year and more than one million deaths directly resulting from the disease. Those at highest risk from the disease are people living in endemic areas, travelers to endemic areas, small children and pregnant women. Malaria is a constant risk to the overall health of the global population. Treatment of malaria depends on the species of infecting parasite, the area where the infection was acquired and its drug resistance status, the clinical status of the patient, any co-morbidities, pregnancy, drug allergies or other medications taken by the patient. Proper treatment of malaria will shorten its duration, prevent complications and help to avoid the majority of deaths. Currently the best available treatment is a combination of drugs known as artemisinin-based combination therapies (ACTs). This therapy works rapidly and has little or no resistance to date. In order to protect against the development we must combine drugs with different mechanisms of action against the same stages of the parasite. Malaria prevention includes vector control, chemoprophylaxis use and the future possibility of vaccine use. Vector control is achieved with the use of insecticide treated mosquito nets and indoor residual spraying of...

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/20709

Permalink: http://www.nusl.cz/ntk/nusl-496660


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Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Master’s theses