Original title: Enzymatic detoxification of cyanide using cyanide hydratases
Authors: Sedova, Anastasia ; Rucká, Lenka ; Glozlová, Michaela ; Novotný, Petr ; Martínková, Ludmila ; Bojarová, Pavla
Document type: Papers
Conference/Event: 15th Annual Doctoral Conference proceedings, Brno (CZ), 20210211
Year: 2021
Language: eng
Abstract: Cyanide, a strong chelator of metals in vital enzymes and proteins, is very toxic for most living organisms. Wastewaters from the mining, metallurgical and chemical industries contain significant concentrations of free cyanide. Though it can be largely eliminated by physicochemical methods, these processes may in turn lead to the formation of other waste. In addition, no effective methods have been found to neutralize cyanide spills coming from industrial accidents. The use of enzymes to remove cyanide is an attractive alternative, which is environmentally friendly and applicable to high cyanide concentrations. Cyanide hydratases (CynHs) are of considerable interest for the decomposition of hazardous cyanide wastes. Here we investigate the biochemical properties of new CynHs from Stereum hirsutum and Exidia glandulosa, it is of fundamental importance to preserve the enzyme activity at alkaline pH as cyanide waste is stored under these conditions.
Keywords: cyanide hydratase; cyanide spills; cyanide waste; free cyanide
Project no.: GA18-00184S (CEP)
Funding provider: GA ČR
Host item entry: New Approaches to State Security Assurance, ISBN 978-80-7582-104-1

Institution: Institute of Microbiology AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0321874

Permalink: http://www.nusl.cz/ntk/nusl-449116


The record appears in these collections:
Research > Institutes ASCR > Institute of Microbiology
Conference materials > Papers