Original title:
Antibacterial electrospun membrane prepared from poly(vinylidene fluoride)-co-hexafluoropropylene with lauric acid monoacylglycerol
Authors:
Zelenková, Jana ; Peer, Petra ; Pleva, P. ; Janalíková, M. ; Sedlaříková, J. ; Filip, Petr Document type: Papers Conference/Event: International Conference NANOCON 2020 /12./, Brno (CZ), 20201021
Year:
2021
Language:
eng Abstract:
The aim of this study was to prepare an antibacterial nanofibrous membrane using electrospinning technique. The nanofibrous membranes were spun from polymer solution of poly(vinylidne fluoride)-co-hexafluoropropylene (PVDF-co-HFP) dissolved in N,N´-dimethylformamide. Monoacylglycerol of lauric acid (MAG C12) was used as an antimicrobial agent at the concentrations ranging from 1 to 3 wt%. The impact of MAG C12 incorporation on the rheological, structural and antibacterial properties was investigated. The rheological tests of polymer solutions, as steady shear and oscillatory shear, proved that addition of MAG C12 changed marginally rheological quantities such as viscosity, elastic (storage) and viscous (loss) moduli. Measurement of mean nanofibres diameter indicated a slight decrease with increasing MAG C12 concentration. Antimicrobial activity of PVDF-co-HFP nanofibre membranes with incorporated MAG C12 against Gram-positive bacteria Staphylococcus aureus and Gram-negative Escherichia coli was studied. An antibacterial activity was revealed for the samples containing MAG C12 at all concentrations against Gram-positive bacteria Staphylococcus aureus by the disk diffusion method.
Keywords:
antibacterial memrane; electrospinning; nanofibres; polymer solution; rheology Project no.: LTC19034 Funding provider: GA MŠk Host item entry: Proceedings 12th International Conference on Nanomaterials - Research & Application - Nanocon 2020, ISBN 978-80-87294-98-7, ISSN 2694-930X Note: Související webová stránka: https://www.confer.cz/nanocon/2020/3741-antibacterial-electrospun-membrane-prepared-from-poly-vinylidene-fluoride-with-lauric-acid-monoacylglycerol
Institution: Institute of Hydrodynamics AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0319057