Original title: Mechanical and structural properties of collagen nanofribrous layers under simulated body conditions
Authors: Říhová, J. ; Suchý, Tomáš ; Vištejnová, L. ; Horný, L. ; Šupová, Monika
Document type: Papers
Conference/Event: Youth Symposium on Experimental Solid Mechanics /17./, Telč (CZ), 20190606
Year: 2019
Language: eng
Abstract: The theme of this paper is the analysis of mechanical and structural properties of nanofibrous COL under simulated body conditions and in the presence of osteoblasts and dermal fibroblasts. COL were prepared by electrostatic spinning of 8 wt% collagen type I dispersion with 8 wt% (to COL) of PEG in phosphate buffer/ethanol solution (1/1 vol). The stability of COL was enhanced by means of cross-linking with EDC and NHS at a molar ratio of 4:1. COL were exposed in culture medium for 21 days and human SAOS-2 human dermal fibroblasts and osteoblasts were cultured therein for 21 days as well.
Keywords: biodegradation; collagen; fibroblasts; mechanical properties; osteoblasts; structural properties
Host item entry: Acta Polytechnica CTU Proceedings, ISBN 978-80-01-06670-6
Note: Související webová stránka: https://ojs.cvut.cz/ojs/index.php/APP/article/view/6031/5306

Institution: Institute of Rock Structure and Mechanics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0313345

Permalink: http://www.nusl.cz/ntk/nusl-432299


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Conference materials > Papers