Original title: Prognostický význam sarkopenie pro pacienty s jaterní cirhózou
Translated title: Prognostic Siginificance of Sarcopenia in Patients with Liver Cirrhosis
Authors: Kozlova, Marina ; Brůha, Radan (advisor) ; Meisnerová, Eva (referee)
Document type: Bachelor's theses
Year: 2020
Language: cze
Abstract: Introduction: Sarcopenia is a common complication of liver cirrhosis and has a significant negative effect on the clinical outcome and prognosis of patients. Sarcopenia is manifested by a loss of muscle mass and a decline in muscle strength and overall physical performance. X-ray examination is the most accurate method in the diagnosis of sarcopenia, but it is unknown to what extent the prognosis of liver cirrhosis can be predicted by non-invasive and broadly available anthropometric measurements and functional tests combined with the analysis of routine laboratory data. The aim of the work is to find factors related to the severity of liver cirrhosis, the occurrence of complications and survival of patients with a focus on muscle mass, muscle strength and physical performance. Methods: The observational study included 20 patients of the IV. Department of Internal Medicine of the General University Hospital in Prague (VFN) - Clinics of Gastroenterology and Hepatology diagnosed with liver cirrhosis. The progress of cirrhosis was assessed with MELD and Child-Pugh scores. Patients were examined twice, once during hospitalization and 3 months later. Functional tests of hand grip strength, chair stand test, NCT test and quality of life questionnaire were performed. Other measurements included...
Keywords: anthropometry; bioimpedance; liver cirrhosis; muscle mass; muscle strength; physical performance; prognosis; sarcopenia; antropometrie; bioimpedance; fyzická výkonnost; jaterní cirhóza; prognóza; sarkopenie; svalová hmota; svalová síla

Institution: Charles University Faculties (theses) (web)
Document availability information: Available in the Charles University Digital Repository.
Original record: http://hdl.handle.net/20.500.11956/118587

Permalink: http://www.nusl.cz/ntk/nusl-415098


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Universities and colleges > Public universities > Charles University > Charles University Faculties (theses)
Academic theses (ETDs) > Bachelor's theses