Original title: Molecular Docking Study Of Potential Drug Candidates Against Borreliosis
Authors: Koščová, Pavlína
Document type: Papers
Language: eng
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: Lyme borreliosis is one of the most common tick-borne infections, for which there is an extensive need to find a new drug. For this purpose our in silico docking study was carried out to identify drug-likeness of chosen small molecules – potential borreliosis drugs. Its results revealed that BesA compound (C2 form) – a membrane fusion protein present in Borrelia burgdorferi, can play a significant role as a possible drug target compound and therefore it should be further examined in development of potential drugs for Lyme borreliosis treatment.
Keywords: Borrelia burgdorferi; borreliosis; Lyme disease; molecular docking; resistance
Host item entry: Proceedings of the 23st Conference STUDENT EEICT 2017, ISBN 978-80-214-5496-5

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/187122

Permalink: http://www.nusl.cz/ntk/nusl-414782


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Conference materials > Papers