Original title: MHC And KIR Genotyping Of Macaques In HIV Infection Research
Authors: Matula, Jan
Document type: Papers
Language: cze
Publisher: Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Abstract: Modern research of viral diseases relies on genomic data processing. Not only is the sequence of a virus important, genomic sequence of specific receptors in affected organisms also plays an important role. In this paper, a novel package for processing of next generation sequencing data in infectious disease written using R/Bioconductor language is proposed. Functionality of the package, including implementation of advanced SSAHA algorithm for fast database searches, in demonstrated using genotyping of genes for MHC and KIR receptors of HIV positive macaques.
Keywords: demultiplexing; genotyping; hash table; HIV; Roche 454; sequencing; SSAHA
Host item entry: Proceedings of the 23st Conference STUDENT EEICT 2017, ISBN 978-80-214-5496-5

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/187026

Permalink: http://www.nusl.cz/ntk/nusl-414686


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Conference materials > Papers